About the Authors

Adrian D. Vickers

avickers@rti.org

Affiliation RTI Health Solutions, Manchester, United Kingdom

Claire Ainsworth

Affiliation RTI Health Solutions, Manchester, United Kingdom

Reema Mody

Current address: Eli Lilly and Co., Indianapolis, Indiana, United States of America

Affiliation Takeda Development Center Americas, Inc., Deerfield, Illinois, United States of America

Annika Bergman

Affiliation Takeda Pharmaceutical GmbH, Zurich, Switzerland

Caroline S. Ling

Affiliation RTI Health Solutions, Manchester, United Kingdom

Jasmina Medjedovic

Affiliation Takeda Pharmaceutical GmbH, Zurich, Switzerland

Michael Smyth

Affiliation Takeda Development Centre Europe Ltd., London, United Kingdom

Competing Interests

Claire Ainsworth, Adrian D. Vickers and Caroline S. Ling are employees of RTI Health Solutions. Annika Bergmann, Jasmina Medjedovic and Michael Smyth are employees of Takeda Pharmaceuticals. Reema Mody was an employee of Takeda Pharmaceuticals during the conduct of the study. This does not alter our adherence to PLOS ONE policies on sharing data and materials.

Author Contributions

Conceptualization: CL RM AB JM. Formal analysis: AV. Funding acquisition: RM. Investigation: CL CA. Methodology: CL CA RM AB. Project administration: CL CA. Software: AV. Supervision: CL RM. Validation: AV. Visualization: CA CL RM AV AB JM MS. Writing – original draft: CA CL. Writing – review & editing: CA CL RM AV AB JM MS.