About the Authors

Paul Kotwinski

p.kotwinski@nhs.net

Affiliations Department of Cardiology, North and East Hertfordshire NHS Trust, Stevenage, United Kingdom, Institute for Human Health and Performance, University College London, London, United Kingdom, NIHR Cardiovascular Biomedical Research Unit, Royal Brompton Hospital and Imperial College, London, United Kingdom

Gillian Smith

Affiliation NIHR Cardiovascular Biomedical Research Unit, Royal Brompton Hospital and Imperial College, London, United Kingdom

Jackie Cooper

Affiliation Centre for Cardiovascular Genetics, University College London, London, United Kingdom

Julie Sanders

Affiliations Institute for Human Health and Performance, University College London, London, United Kingdom, Barts Heart Centre, St Bartholemew’s Hospital, Barts Health NHS Trust, London, United Kingdom

Louise Ma

Affiliation Institute for Human Health and Performance, University College London, London, United Kingdom

Albert Teis

Affiliations NIHR Cardiovascular Biomedical Research Unit, Royal Brompton Hospital and Imperial College, London, United Kingdom, Cardiovascular Imaging Unit, Cardiology Department, Germans Trias i Pujol University Hospital, Badalona. Barcelona, Spain

David Kotwinski

Affiliations Institute for Human Health and Performance, University College London, London, United Kingdom, The Anaesthetic Department, Derriford Hospital, Plymouth, United Kingdom

Michael Mythen

Affiliations Department of Anaesthesia and Critical Care, University College London Hospital, London, United Kingdom, UCL Institute of Cardiovascular Science and NIHR University College London Hospitals Biomedical Research Centre, London, United Kingdom

Dudley J. Pennell

Affiliation NIHR Cardiovascular Biomedical Research Unit, Royal Brompton Hospital and Imperial College, London, United Kingdom

Alison Jones

Affiliation LOC, London, United Kingdom

Hugh Montgomery

Affiliations Institute for Human Health and Performance, University College London, London, United Kingdom, UCL Institute of Cardiovascular Science and NIHR University College London Hospitals Biomedical Research Centre, London, United Kingdom

on behalf of the Breast cancer Early disease: Toxicity from Therapy with Epirubicin Regimens–Cardiac Assessment and Risk Evaluation (BETTER-CARE) Study Investigators

The BETTER-CARE Study Investigators are listed in the Acknowledgments

Competing Interests

The authors PK, JS, LM, AT, DK and HM declare they have no not competing interests. DJP receives research funding from Siemens Medical Systems, (Erlangen, Germany), and is a shareholder and director of Cardiovascular Imaging Solutions (London, UK). This does not alter our adherence to PLOS ONE policies on sharing data and materials. AJ is employed by Leaders in Oncology (LOC, London, UK). An affiliation which commenced after this study was complete. This does not alter our adherence to PLOS ONE policies on sharing data and materials. MM declares no completing interests in relation to this study. He declares commercial affiliations which have no relation to this study: paid Consultant Princes Grace Hospital London; Paid Consultant for Deltex; Paid Consultant for Edwards LifeSciences; Consultant Bev MD; University Chair Sponsor at UCL by Smiths Medical; Director Medinspire Ltd; Share holder and Scientific Advisor Medical Defense Technologies LLC (Gastrostim and Entarik); Director QUENCH ltd (Patent holder “QUENCH”). These do not alter our adherence to PLOS ONE policies on sharing data and materials.

Author Contributions

Conceptualization: PK GS MM DJP AJ HM. Data curation: PK GS JS AT DK. Formal analysis: PK JC HM. Funding acquisition: PK JC MM DJP AJ HM. Investigation: PK GS JS LM AT AJ. Methodology: PK GS DK DJP AJ HM. Project administration: PK GS JS. Resources: MM DJP HM. Supervision: MM DJP HM. Validation: DJP HM. Writing – original draft: PK JC JS DJP AJ HM. Writing – review & editing: PK GS JC JS LM AT DK MM DJP AJ HM.