About the Authors

Robert Froud

r.froud@warwick.ac.uk

Affiliations Department of Health Sciences, Kristiania University College, Oslo, Norway, Warwick Medical School, University of Warwick, Coventry, United Kingdom

Shilpa Patel

Affiliation Warwick Medical School, University of Warwick, Coventry, United Kingdom

Dévan Rajendran

Contributed equally to this work with: Dévan Rajendran, Philip Bright, Tom Bjørkli

Affiliation European School of Osteopathy, Maidstone, Kent, United Kingdom

Philip Bright

Contributed equally to this work with: Dévan Rajendran, Philip Bright, Tom Bjørkli

Affiliation European School of Osteopathy, Maidstone, Kent, United Kingdom

Tom Bjørkli

Contributed equally to this work with: Dévan Rajendran, Philip Bright, Tom Bjørkli

Affiliation Department of Health Sciences, Kristiania University College, Oslo, Norway

Rachelle Buchbinder

Affiliation Monash Department of Clinical Epidemiology, Cabrini Institute and Department of Epidemiology and Preventive Medicine, School of Public Health and Preventative Medicine, Monash University, Malvern, Victoria, Australia

Sandra Eldridge

Affiliation Barts and the London School of Medicine and Dentistry, Queen Mary University of London, London, United Kingdom

Martin Underwood

Affiliation Warwick Medical School, University of Warwick, Coventry, United Kingdom

Competing Interests

The authors have declared that no competing interests exist, apart from RF and MU who have read the journal’s policy and the authors of this manuscript have the following competing interests: They are shareholders and directors of Clinvivo Ltd, a company that provides electronic outcome measurement services. MU declares that he is lead author on two of the 401 trials included in this systematic review. This does not alter our adherence to PLOS ONE policies on sharing data and materials.

Author Contributions

Conceptualization: RF MU SE RB. Data curation: RF PB DR TB. Formal analysis: RF. Funding acquisition: RF MU SE RB. Investigation: RF SP TB PB DR SE RB MU. Methodology: RF MU SE RB. Project administration: RF. Software: RF. Supervision: RF SE RB MU. Validation: RF SP TB PB DR SE. Visualization: RF DR MU. Writing – original draft: RF. Writing – review & editing: RF SP TB PB DR SE RB MU.