About the Authors

Dominik Domanski

Contributed equally to this work with: Dominik Domanski, Oliwia Zegrocka-Stendel

Affiliation Laboratory of Mass Spectrometry, Institute of Biochemistry and Biophysics, Polish Academy of Sciences, Warsaw, Poland

Oliwia Zegrocka-Stendel

Contributed equally to this work with: Dominik Domanski, Oliwia Zegrocka-Stendel

Affiliation Centre for Preclinical Research and Technology, Department of Immunology, Biochemistry and Nutrition, Medical University of Warsaw, Warsaw, Poland

Anna Perzanowska

Affiliation Laboratory of Mass Spectrometry, Institute of Biochemistry and Biophysics, Polish Academy of Sciences, Warsaw, Poland

Malgorzata Dutkiewicz

Affiliation Centre for Preclinical Research and Technology, Department of Immunology, Biochemistry and Nutrition, Medical University of Warsaw, Warsaw, Poland

Magdalena Kowalewska

Affiliation Department of Molecular and Translational Oncology, Maria Sklodowska-Curie Memorial Cancer Center and Institute of Oncology, Warsaw, Poland

Iwona Grabowska

Affiliation Department of Cytology, Faculty of Biology, University of Warsaw, Warsaw, Miecznikowa 1, 02–096 Warsaw, Poland

Dorota Maciejko

Affiliation Centre for Preclinical Research and Technology, Department of Immunology, Biochemistry and Nutrition, Medical University of Warsaw, Warsaw, Poland

Anna Fogtman

Affiliation Laboratory for Microarray Analysis CORELAB, Institute of Biochemistry and Biophysics, Polish Academy of Sciences, Warsaw, Poland

Michal Dadlez

Affiliation Laboratory of Mass Spectrometry, Institute of Biochemistry and Biophysics, Polish Academy of Sciences, Warsaw, Poland

Katarzyna Koziak

katarzyna.koziak@wum.edu.pl

Affiliation Centre for Preclinical Research and Technology, Department of Immunology, Biochemistry and Nutrition, Medical University of Warsaw, Warsaw, Poland

Competing Interests

DD, OZ-S, DM, MK and KK have a potential financial competing interest related to a patent application EP15001035.3 “New therapy for Alzheimer’s disease. OZ-S, IG, DM, MK and KK have a potential financial competing interest related to a patent application PCT/IB2016/000187 “Protoescigenin derivative, process of its preparation, use of said compound and pharmaceutical composition comprising that compound. This does not alter our adherence to PLOS ONE policies on sharing data and materials.

Author Contributions

Conceptualization: DD OZ-S MK IG DM AF MDa KK. Data curation: DD AP MK IG AF KK. Formal analysis: MK KK. Funding acquisition: DD KK. Investigation: DD OZ-S AP MDu MK IG DM AF MDa KK. Methodology: DD OZ-S AP MDu MK IG DM AF MDa KK. Project administration: DM MK KK. Supervision: MK MDa KK. Validation: DD AP OZ-S IG MDu AF MDa KK. Visualization: IG MK KK. Writing – original draft: DD OZ-S AP MDu MK IG DM AF MDa KK. Writing – review & editing: MK KK.