About the Authors

Paul H. Axelsen

axe@pharm.med.upenn.edu.

Affiliation Departments of Pharmacology, Biochemistry and Biophysics, and Medicine, University of Pennsylvania School of Medicine, Philadelphia, PA, 19104–6084, United States of America

Robert C. Murphy

Affiliation Department of Pharmacology, Mail Stop 8303, University of Colorado at Denver Health Sciences Center, Aurora, CO, 80045–0511, United States of America

Miki Igarashi

Current address: Riken Yokohama Branch, Center for Integrative Medical Sciences, 1-7-22 Suehiro-cho, Tsurumi-ku, Yokohama City Kanagawa, 230–0045, Japan

Affiliation Brain Physiology and Metabolism Section, National Institute on Aging, National Institutes of Health, Bethesda, MD, 20892, United States of America

Stanley I. Rapoport

Affiliation Brain Physiology and Metabolism Section, National Institute on Aging, National Institutes of Health, Bethesda, MD, 20892, United States of America

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceptualization: PHA RCM MI SIR. Formal analysis: PHA. Funding acquisition: PHA SIR RCM. Methodology: PHA RCM. Resources: PHA RCM MI SIR. Writing – original draft: PHA.