About the Authors

Hiroshi Nomoto

Affiliation Division of Rheumatology, Endocrinology and Nephrology, Hokkaido University Graduate School of Medicine, Sapporo, Japan

Hideaki Miyoshi

hmiyoshi@med.hokudai.ac.jp

Affiliation Division of Rheumatology, Endocrinology and Nephrology, Hokkaido University Graduate School of Medicine, Sapporo, Japan

Tomoo Furumoto

Affiliations Department of Cardiovascular Medicine, NTT East Japan Sapporo Hospital, Sapporo, Japan, Department of Cardiovascular Medicine, Hokkaido University Graduate School of Medicine, Sapporo, Japan

Koji Oba

Affiliations Department of Biostatistics, School of Public Health, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan, Interfaculty Initiative in Information Studies, The University of Tokyo, Tokyo, Japan

Hiroyuki Tsutsui

Affiliation Department of Cardiovascular Medicine, Hokkaido University Graduate School of Medicine, Sapporo, Japan

Atsushi Inoue

Affiliation Japan Community Healthcare and Organization Hokkaido Hospital, Sapporo, Japan

Tatsuya Atsumi

Affiliation Division of Rheumatology, Endocrinology and Nephrology, Hokkaido University Graduate School of Medicine, Sapporo, Japan

Naoki Manda

Affiliation Manda Memorial Hospital, Sapporo, Japan

Yoshio Kurihara

Affiliation Kurihara Clinic, Sapporo, Japan

Shin Aoki

‡ SA is the lead author for this group.

Affiliation Aoki Clinic, Sapporo, Japan

on behalf of SAIS Study Group

Membership of SAIS Study Group is provided in the Acknowledgments.

Competing Interests

I have read the journal's policy and the authors of this manuscript have the following competing interests: H. Miyoshi has received honoraria for lectures from Astellas, AstraZeneca, Dainippon Pharma, Eli Lilly, Kissei, Mitsubishi Tanabe Pharma, MSD, Novartis, Novo Nordisk and Sanofi; and received scholarship grants from Astellas, AstraZeneca, Daiichi Sankyo, Eli Lilly, Mitsubishi Tanabe Pharma, MSD, Novo Nordisk, Sanofi, Takeda and Taisho Pharmaceutical Co., Ltd. T. Atsumi has received honoraria for lectures from Takeda Pharmaceutical, Mitsubishi Tanabe Pharma, Pfizer, Eisai, Avvie, UCB Japan, Astellas Pharma and Chugai Pharmaceutical Co., Ltd; and received research grants from Astellas, Chugai, Sanofi, Eisai, Alexion, Bristol-Myers Squibb, Mitsubishi Tanabe Pharma and Janssen Pharmaceutical K.K.; and received scholarship grants from Astellas, Takeda, Mitsubishi Tanabe Pharma, Chugai, Daiichi Sankyo, Eisai and Bayer, Ltd. This does not alter our adherence to PLOS ONE policies on sharing data and materials.

Author Contributions

Conceptualization: HN HM. Data curation: HN KO. Formal analysis: HN KO. Funding acquisition: HM. Investigation: HN TF AI NM YK. Methodology: HN HM. Project administration: SA. Supervision: HM TA SA. Validation: HM KO TA. Visualization: HN. Writing – original draft: HN. Writing – review & editing: HM TA HT.