About the Authors

Lele Song

Contributed equally to this work with: Lele Song, Yuemin Li

songlele@sina.com (LS); shan@biochain.com (XH)

Affiliation The Chinese PLA 309th hospital, Beijing, People’s Republic of China

Yuemin Li

Contributed equally to this work with: Lele Song, Yuemin Li

Affiliation The Chinese PLA 309th hospital, Beijing, People’s Republic of China

Jia Jia

Affiliation The Chinese PLA 309th hospital, Beijing, People’s Republic of China

Guangpeng Zhou

Affiliation BioChain (Beijing) Science and Technology, Inc, Beijing, People’s Republic of China

Jianming Wang

Affiliation BioChain (Beijing) Science and Technology, Inc, Beijing, People’s Republic of China

Qian Kang

Affiliation Department of Gastroenterology, The Army General Hospital, Beijing, People’s Republic of China

Peng Jin

Affiliation Department of Gastroenterology, The Army General Hospital, Beijing, People’s Republic of China

Jianqiu Sheng

Affiliation Department of Gastroenterology, The Army General Hospital, Beijing, People’s Republic of China

Guoxiang Cai

Affiliation Department of Colorectal Surgery, Fudan University Shanghai Cancer Center, Shanghai, People’s Republic of China

Sanjun Cai

Affiliation Department of Colorectal Surgery, Fudan University Shanghai Cancer Center, Shanghai, People’s Republic of China

Xiaoliang Han

songlele@sina.com (LS); shan@biochain.com (XH)

Affiliation BioChain (Beijing) Science and Technology, Inc, Beijing, People’s Republic of China

Competing Interests

This study was supported by BioChain (Beijing) Science and Technology, Inc. Dr. Lele Song, Dr. Guangpeng Zhou, Mr. Jianming Wang and Dr. Xiaoliang Han are current employees of BioChain (Beijing) Science and Technology, Inc. BioChain is a collaborator of Epigenomics AG, a Germany-based company that launched the first commercial SEPT9 assay. There are no patents, products in development or marketed products to declare. This does not alter our adherence to all the PLOS ONE policies on sharing data and materials, as detailed online in the guide for authors. Other authors claim no conflict of interests.

Author Contributions

Conceptualization: LS GZ JW SC JS XH. Data curation: LS JJ GZ QK PJ GC XH. Formal analysis: LS GZ QK PJ GC XH. Funding acquisition: LS YL GZ JW XH. Investigation: LS YL JJ GZ QK PJ GC XH. Methodology: GZ JW XH. Project administration: YL SC JS XH. Resources: GZ JW XH. Software: GZ JW XH. Supervision: YL SC JS XH. Validation: GZ YL JJ JW XH. Visualization: LS XH. Writing – original draft: LS XH. Writing – review & editing: LS XH.