About the Authors

Terence G. Hall

thall@arqule.com

Affiliation ArQule, Inc., Burlington, MA, United States of America

Yi Yu

Affiliation ArQule, Inc., Burlington, MA, United States of America

Sudharshan Eathiraj

Affiliation ArQule, Inc., Burlington, MA, United States of America

Yunxia Wang

Affiliation ArQule, Inc., Burlington, MA, United States of America

Ronald E. Savage

Affiliation ArQule, Inc., Burlington, MA, United States of America

Jean-Marc Lapierre

Affiliation ArQule, Inc., Burlington, MA, United States of America

Brian Schwartz

Affiliation ArQule, Inc., Burlington, MA, United States of America

Giovanni Abbadessa

Affiliation ArQule, Inc., Burlington, MA, United States of America

Competing Interests

TGH, RES, YY, SE, TH, GA, JS, and BS are employees of ArQule, Inc. KP and WS have no competing financial interests. This does not alter the authors' adherence to PLOS ONE policies on sharing data and materials.

Author Contributions

Conceptualization: TH YY SE YW RS JML BS GA. Formal analysis: TH SE. Funding acquisition: GA BS. Investigation: TH YY SE YW. Methodology: TH YY SE. Project administration: GA. Supervision: GA BS. Validation: TH YY SE YW. Visualization: TH ES. Writing – original draft: TH YY ES RS JML. Writing – review & editing: TH YY SE RS JML GA.