About the Authors

Diletta Magini

Current address: Division of Immunology, Transplantation and Infectious Diseases, IRCCS San Raffaele Scientific Institute, Milano, Italy

Affiliations Novartis Vaccines, S.r.l., Siena, Italy, Dipartimento di Biotecnologie, Chimica e Farmacia, Università degli Studi di Siena, Siena, Italy

Cinzia Giovani

Current address: GSK Vaccines S.r.l., Siena, Italy

Affiliation Novartis Vaccines, S.r.l., Siena, Italy

Simona Mangiavacchi

Current address: GSK Vaccines S.r.l., Siena, Italy

Affiliation Novartis Vaccines, S.r.l., Siena, Italy

Silvia Maccari

Current address: GSK Vaccines S.r.l., Siena, Italy

Affiliation Novartis Vaccines, S.r.l., Siena, Italy

Raffaella Cecchi

Current address: GSK Vaccines S.r.l., Siena, Italy

Affiliation Novartis Vaccines, S.r.l., Siena, Italy

Jeffrey B. Ulmer

Current address: GSK Vaccines Inc., Cambridge, MA, United States of America

Affiliation Novartis Vaccines Inc., Cambridge, MA, United States of America

Ennio De Gregorio

Current address: GSK Vaccines S.r.l., Siena, Italy

Affiliation Novartis Vaccines, S.r.l., Siena, Italy

Andrew J. Geall

Current address: Avidity NanoMedicines LLC, San Diego, CA, United States of America

Affiliation Novartis Vaccines Inc., Cambridge, MA, United States of America

Michela Brazzoli

michela.x.brazzoli@gsk.com

Current address: GSK Vaccines S.r.l., Siena, Italy

Affiliation Novartis Vaccines, S.r.l., Siena, Italy

Sylvie Bertholet

Current address: GSK Vaccines S.r.l., Siena, Italy

Affiliation Novartis Vaccines, S.r.l., Siena, Italy

Competing Interests

All the authors were employed or affiliated with the Novartis group of companies at the time of study conduct. CG, SMg, SMc, RC, JBU, EDG, MB and SB are now employeed with GSK group companies; AJG is now employed with Avidity NanoMedicine. All the authors declare that they have no other relevant affiliations or financial interest in conflict with the subject matter or materials discussed in the manuscript. All the authors declare that SAM technology is covered by a registered patent (reference number: WO2012006376).

Author Contributions

Conceived and designed the experiments: DM MB SB. Performed the experiments: DM MB. Analyzed the data: DM MB. Contributed reagents/materials/analysis tools: CG S. Mangiavacchi S. Maccari RC. Wrote the paper: DM MB SB JBU EDG AJG. Strategic support: AJG JBU EDG.