About the Authors

Emily J. Guggenheim

Affiliations Physical Science of Imaging in the Biomedical Sciences (PSIBS) Doctoral Training Centre (DTC), Birmingham, Edgbaston, United Kingdom, School of Biosciences, University of Birmingham, Edgbaston, Birmingham, United Kingdom

Abdullah Khan

Affiliation School of Biosciences, University of Birmingham, Edgbaston, Birmingham, United Kingdom

Jeremy Pike

Affiliations Physical Science of Imaging in the Biomedical Sciences (PSIBS) Doctoral Training Centre (DTC), Birmingham, Edgbaston, United Kingdom, School of Biosciences, University of Birmingham, Edgbaston, Birmingham, United Kingdom

Lynne Chang

Affiliation Nikon Instruments, Inc. Melville, New York, United States of America

Iseult Lynch

Affiliation School of Geography, Earth and Environmental Sciences, University of Birmingham, Edgbaston, United Kingdom

Joshua Z. Rappoport

joshua.rappoport@northwestern.edu

Affiliation Center for Advanced Microscopy, and Nikon Imaging Center, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, United States of America

Competing Interests

LC is an employee of Nikon Instruments. Although Nikon had no role in the funding or oversight of the studies presented, this could be indicative of an indirect COI. This does not alter our adherence to PLOS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: EJG LC IL JZR. Performed the experiments: EJG AK. Analyzed the data: EJG IL JZR. Contributed reagents/materials/analysis tools: EJG IL JZR JP. Wrote the paper: EJG IL JZR.