About the Authors

Tomasz Fundament

Affiliation HTA Consulting, Krakow, Poland

Paul R. Eldridge

Affiliation The Walton Centre NHS Foundation Trust and Liverpool University, Liverpool, United Kingdom

Alexander L. Green

alex.green@nds.ox.ac.uk

Affiliation Nuffield Department of Surgical Sciences, University of Oxford, Oxford, United Kingdom

Alan L. Whone

Affiliation Bristol Brain Centre, Southmead Hospital, Bristol, United Kingdom

Rod S. Taylor

Affiliation University of Exeter Medical School, Exeter, United Kingdom

Adrian C. Williams

Affiliation University Hospitals Birmingham NHS Foundation Trust, Birmingham, United Kingdom

W. M. Michael Schuepbach

Affiliations Movement Disorders Center, Department of Neurology, Bern University Hospital and University of Bern, Bern, Switzerland, Assistance Publique Hôpitaux de Paris, Centre d’Investigation Clinique 9503, Institut du Cerveau et de la Moelle épinière, Département de Neurologie, Université Pierre et Marie Curie–Paris 6 et INSERM, CHU Pitié-Salpêtrière, Paris, France

Competing Interests

The authors of this manuscript have read the journal’s policy and have the following competing interests: Medtronic funded the development of the model. TF is an employee of HTA Consulting, a health economic consultancy firm that received consulting fees from Medtronic International Sàrl for their work on this project. PRE has received honoraria for consulting services and meeting sponsorship from Medtronic, St. Jude Medical, Boston Scientific and Nevro. He has also served as a member of the UK adult commissioning group for Neurosurgery. ALG has received honoraria for consulting services from Medtronic, St. Jude Medical and Boston Scientific. Over the last 12 months, he has also been faculty on two St. Jude Medical courses (DRG stimulation) and attended an advisory board with Boston Scientific. ALW has received honoraria from Medtronic for consulting services. ACW has received honoraria from Medtronic for consulting services. RST has received honoraria from Medtronic for consulting services. WMMS has received lecture fees from Medtronic, and travel reimbursements from Merz Pharma, Boston Scientific, Actelion, Zambon and Medtronic. He has been serving as a consultant for Medtronic, Aleva, Zambon and Lundbeck. He has received unrestricted research grants from Medtronic, Boston Scientific and Actelion. There are no patents, products in development or marketed products to declare. This does not alter the authors’ adherence to all PLOS ONE policies on sharing data and materials, as detailed online in the guide for authors.

Author Contributions

Conceived and designed the experiments: TF PRE ALG ALW RST ACW WMMS. Analyzed the data: TF. Wrote the paper: TF PRE ALG ALW RST ACW WMMS. Model development: TF. Interpretation of data: TF PRE ALG ALW RST ACW WMMS.