About the Authors

Thaminda Liyanage

Affiliations The George Institute for Global Health, Sydney Medical School, University of Sydney, PO Box M201, Missenden Road, Sydney, NSW, 2050, Australia, Armadale Kelmscott Memorial Hospital, South Metropolitan Health Service, Armadale, WA, 6112, Australia

Toshiharu Ninomiya

tninomiya@georgeinstitute.org.au

Affiliation The George Institute for Global Health, Sydney Medical School, University of Sydney, PO Box M201, Missenden Road, Sydney, NSW, 2050, Australia

Amanda Wang

Affiliation The George Institute for Global Health, Sydney Medical School, University of Sydney, PO Box M201, Missenden Road, Sydney, NSW, 2050, Australia

Bruce Neal

Affiliation The George Institute for Global Health, Sydney Medical School, University of Sydney, PO Box M201, Missenden Road, Sydney, NSW, 2050, Australia

Min Jun

Affiliations The George Institute for Global Health, Sydney Medical School, University of Sydney, PO Box M201, Missenden Road, Sydney, NSW, 2050, Australia, Department of Medicine, Division of Nephrology, University of Calgary, Calgary, Alberta, Canada

Muh Geot Wong

Affiliations The George Institute for Global Health, Sydney Medical School, University of Sydney, PO Box M201, Missenden Road, Sydney, NSW, 2050, Australia, Armadale Kelmscott Memorial Hospital, South Metropolitan Health Service, Armadale, WA, 6112, Australia

Meg Jardine

Affiliations The George Institute for Global Health, Sydney Medical School, University of Sydney, PO Box M201, Missenden Road, Sydney, NSW, 2050, Australia, Concord Repatriation General Hospital, Hospital Road, Concord, Sydney, NSW, 2139, Australia

Graham S. Hillis

Affiliation The George Institute for Global Health, Sydney Medical School, University of Sydney, PO Box M201, Missenden Road, Sydney, NSW, 2050, Australia

Vlado Perkovic

Affiliation The George Institute for Global Health, Sydney Medical School, University of Sydney, PO Box M201, Missenden Road, Sydney, NSW, 2050, Australia

Competing Interests

The authors have read the journal's policy and the authors of this manuscript have the following competing interests. Thaminda Liyanage, Toshiharu Ninomiya, Amanda Wong, Min Jun and Muh Geot Wong have no conflicts of interests to declare. Vlado Perkovic has no conflicts of interest related to this work, but has served on advisory boards and/or received funding for trials from Abbvie, Astellas, Astra Zeneca, Baxter, Boehringer Ingelheim, GSK, Janssen, Pfizer, Roche, Servier, and Vitae. Meg Jardine has no conflicts of interest related to this work but has received funding for trials from Baxter, Gambro, Shire and Janssen. Bruce Neal has no conflicts of interest related to this work but has served on advisory boards and/or received funding for trials from Abbott, Abbvie, Australian Food and Grocery Council, Bupa Australia, Compumedics, Dr Reddy’s Laboratories, Janssen, Novartis, Pharmacy Guild of Australia, ResMed, Roche, Servier and United Healthcare Group. Graham Hillis has no conflicts of interest related to this work but has received research funding support or served on advisory boards, trial steering or end-point adjudication committees for Astra Zeneca, Biotronik, Boehringer Ingelheim, Bristol-Myers Squibb, BUPA Australia, Janssen, and Pfizer. This does not alter the authors’ adherence to PLOS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: TL TN AW M. Jun VP. Analyzed the data: TL TN AW M. Jun VP. Wrote the paper: TL TN BN M. Jun M. Jardine VP. Data interpretation and critical revision of manuscript: TL TN AW BN M. Jun MW M. Jardine GH VP.