Assessment of Anti-TNF-α Activities in Keratinocytes Expressing Inducible TNF- α: A Novel Tool for Anti-TNF-α Drug Screening

Sutthirat Udommethaporn; Tewin Tencomnao; Eileen M. McGowan; Viroj Boonyaratanakornkit

doi:10.1371/journal.pone.0159151

Loading metrics

Open Access

Peer-reviewed

Research Article

Assessment of Anti-TNF-α Activities in Keratinocytes Expressing Inducible TNF- α: A Novel Tool for Anti-TNF-α Drug Screening

Sutthirat Udommethaporn,

Affiliation Graduate Program in Clinical Biochemistry and Molecular Medicine, Faculty of Allied Health Sciences, Chulalongkorn University, Bangkok 10330, Thailand
⨯
Tewin Tencomnao,

Affiliations Graduate Program in Clinical Biochemistry and Molecular Medicine, Faculty of Allied Health Sciences, Chulalongkorn University, Bangkok 10330, Thailand, Department of Clinical Chemistry, Faculty of Allied Health Sciences, Chulalongkorn University, Bangkok 10330, Thailand
⨯
Eileen M. McGowan,

Affiliation Chronic Disease Solutions Team, School of Life Sciences, University of Technology Sydney, Ultimo, 2007, Sydney, Australia
⨯
Viroj Boonyaratanakornkit

* E-mail: Viroj.b@chula.ac.th

Affiliations Graduate Program in Clinical Biochemistry and Molecular Medicine, Faculty of Allied Health Sciences, Chulalongkorn University, Bangkok 10330, Thailand, Department of Clinical Chemistry, Faculty of Allied Health Sciences, Chulalongkorn University, Bangkok 10330, Thailand

http://orcid.org/0000-0003-1800-7836

⨯

Assessment of Anti-TNF-α Activities in Keratinocytes Expressing Inducible TNF- α: A Novel Tool for Anti-TNF-α Drug Screening

Sutthirat Udommethaporn,
Tewin Tencomnao,
Eileen M. McGowan,
Viroj Boonyaratanakornkit

Published: July 14, 2016
https://doi.org/10.1371/journal.pone.0159151

About the Authors

Sutthirat Udommethaporn

Affiliation Graduate Program in Clinical Biochemistry and Molecular Medicine, Faculty of Allied Health Sciences, Chulalongkorn University, Bangkok 10330, Thailand

Tewin Tencomnao

Affiliations Graduate Program in Clinical Biochemistry and Molecular Medicine, Faculty of Allied Health Sciences, Chulalongkorn University, Bangkok 10330, Thailand, Department of Clinical Chemistry, Faculty of Allied Health Sciences, Chulalongkorn University, Bangkok 10330, Thailand

Eileen M. McGowan

Affiliation Chronic Disease Solutions Team, School of Life Sciences, University of Technology Sydney, Ultimo, 2007, Sydney, Australia

Viroj Boonyaratanakornkit

* E-mail: Viroj.b@chula.ac.th

http://orcid.org/0000-0003-1800-7836

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: VB TT. Performed the experiments: SU. Analyzed the data: SU VB EM. Contributed reagents/materials/analysis tools: EM TT. Wrote the paper: SU VB EM.

Subject Areas
?

For more information about PLOS Subject Areas, click here.
We want your feedback. Do these Subject Areas make sense for this article? Click the target next to the incorrect Subject Area and let us know. Thanks for your help!

Cytokine therapy
Is the Subject Area "Cytokine therapy" applicable to this article?

Thanks for your feedback.
Cytokines
Is the Subject Area "Cytokines" applicable to this article?

Thanks for your feedback.
Cell membranes
Is the Subject Area "Cell membranes" applicable to this article?

Thanks for your feedback.
Keratinocytes
Is the Subject Area "Keratinocytes" applicable to this article?

Thanks for your feedback.
Gene expression
Is the Subject Area "Gene expression" applicable to this article?

Thanks for your feedback.
Psoriasis
Is the Subject Area "Psoriasis" applicable to this article?

Thanks for your feedback.
Membrane proteins
Is the Subject Area "Membrane proteins" applicable to this article?

Thanks for your feedback.
Inflammatory bowel disease
Is the Subject Area "Inflammatory bowel disease" applicable to this article?

Thanks for your feedback.