About the Authors

Hong Wang

Affiliations Department of Stomatology, General Hospital of the People’s Libration Army, Beijing, China, Department of Stomatology, the Second Affiliated Stomatological Hospital of Liaoning Medical University, Jinzhou, China

Bingjing Zhao

Affiliations Department of Stomatology, General Hospital of the People’s Libration Army, Beijing, China, Department of Stomatology, the Second Affiliated Stomatological Hospital of Liaoning Medical University, Jinzhou, China

Changkui Liu

Affiliation Department of Stomatology, the 451th Hospital of the People’s Libration Army, Xi’an, China

Chao Wang

Affiliation School of Medicine, Nankai University, Tianjin, China

Xinying Tan

Affiliation Department of Stomatology, the 304th Hospital of the People’s Libration Army, Beijing, China

Min Hu

humin48@vip.163.com

Affiliation Department of Stomatology, General Hospital of the People’s Libration Army, Beijing, China

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: MH. Performed the experiments: HW BZ. Analyzed the data: HW XT. Contributed reagents/materials/analysis tools: HW BZ CL CW. Wrote the paper: HW BZ. Executed the cell culture, cell studies, animal studies, data analyses and manuscript organization: HW. Carried out the metal samples fabrication, animals studies and manuscript organization: BZ. Contributed equal to this project: HW BZ. Contributed to assistance of the animal studies: CL CW. Contributed to assisstance of data collection and analyses: XT. Responsible for the overall study design and planning: MH.