About the Authors

Craig I. Coleman

craig.coleman@hhchealth.org

Affiliation University of Connecticut School of Pharmacy, Storrs, Connecticut, United States of America

Muralikrishna Tangirala

Affiliation Bayer HealthCare Pharmaceuticals, Whippany, New Jersey, United States of America

Thomas Evers

Affiliation Bayer Pharma AG, Wuppertal, Germany

Competing Interests

The authors have the following interests. Funding for this study was provided by Bayer HealthCare Pharmaceuticals and Janssen Scientific Affairs, LLC. Muralikrishna Tangirala is employed by Bayer HealthCare Pharmaceuticals and Thomas Evers by Bayer Pharma AG. Rivaroxaban is manufactured by Bayer. There are no further patents, products in development or marketed products to declare. This does not alter the authors' adherence to all the PLOS ONE policies on sharing data and materials, as detailed online in the guide for authors.

Author Contributions

Conceived and designed the experiments: CC MT TE. Performed the experiments: MT. Analyzed the data: MT. Wrote the paper: CC MT TE.