About the Authors

Hu Sheng Qian

husheng.qian@boehringer-ingelheim.com

Affiliation CardioMetabolic Disease Research, Boehringer Ingelheim Pharmaceutics, Inc, Ridgefield, Connecticut, United States of America

Steve M. Weldon

Affiliation CardioMetabolic Disease Research, Boehringer Ingelheim Pharmaceutics, Inc, Ridgefield, Connecticut, United States of America

Damian Matera

Affiliation CardioMetabolic Disease Research, Boehringer Ingelheim Pharmaceutics, Inc, Ridgefield, Connecticut, United States of America

ChungWein Lee

Affiliation CardioMetabolic Disease Research, Boehringer Ingelheim Pharmaceutics, Inc, Ridgefield, Connecticut, United States of America

Haichun Yang

Affiliation Department of Pathology, Microbiology and Immunology, Vanderbilt University School of Medicine, Nashville, Tennessee, United States of America

Ryan M. Fryer

Affiliation CardioMetabolic Disease Research, Boehringer Ingelheim Pharmaceutics, Inc, Ridgefield, Connecticut, United States of America

Agnes B. Fogo

Affiliation Department of Pathology, Microbiology and Immunology, Vanderbilt University School of Medicine, Nashville, Tennessee, United States of America

Glenn A. Reinhart

Affiliation CardioMetabolic Disease Research, Boehringer Ingelheim Pharmaceutics, Inc, Ridgefield, Connecticut, United States of America

Competing Interests

No competing interests exist, and the commercial affiliation, Boehringer Ingelheim Pharmaceutics, Inc, does not alter the authors' adherence to all PLOS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: HSQ SMW. Performed the experiments: DM HCY. Analyzed the data: HSQ DM CWL HCY. Wrote the paper: HSQ GAR SMW RMF ABF DM CWL HCY.