About the Authors

Birgit Grund

birgit@ccbr.umn.edu

Affiliation School of Statistics, University of Minnesota, Minneapolis, MN, United States of America

Jason V Baker

Affiliations Hennepin County Medical Center, Minneapolis, MN, United States of America, Department of Medicine, University of Minnesota, Minneapolis, MN, United States of America

Steven G. Deeks

Affiliations University of California San Francisco, San Francisco, CA, United States of America, San Francisco General Hospital, San Francisco, CA, United States of America

Julian Wolfson

Affiliation Division of Biostatistics, School of Public Health, University of Minnesota, Minneapolis, MN, United States of America

Deborah Wentworth

Affiliation Division of Biostatistics, School of Public Health, University of Minnesota, Minneapolis, MN, United States of America

Alessandro Cozzi-Lepri

Affiliation University College London, London, United Kingdom

Calvin J. Cohen

Affiliation Medical Affairs Department, Gilead Sciences, Foster City, CA, United States of America

Andrew Phillips

Affiliation University College London, London, United Kingdom

Jens D. Lundgren

Affiliation Department of Infectious Diseases, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark

James D. Neaton

Affiliation Division of Biostatistics, School of Public Health, University of Minnesota, Minneapolis, MN, United States of America

INSIGHT SMART/ESPRIT/SILCAAT Study Group

Complete membership of the author group can be found in the Acknowledgments.

Competing Interests

The authors have the following potentially competing interests: AP received fees for speaking from Gilead Sciences, consulting from GSK Biologicals, and advisory board membership from AbbVie. CJC is currently receiving salary support from Gilead Sciences. The other authors reported no competing interests. While the SILCAAT and ESPRIT trials were supported by Chiron-Novartis, none of the authors received salary support from Chiron-Novartis, or have any competing interests with respect to ChironNovartis. The potentially competing interests do not alter the authors’ adherence to PLOS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: BG JVB SGD JW CJC AP JDL JDN. Analyzed the data: BG DW. Wrote the paper: BG JVB SGD JW CJC AC-L AP JDL JDN.