About the Authors

Yue Li

Affiliation Department of Integrative Biology and Pharmacology, The University of Texas Health Science Center at Houston, Houston, TX, 77030, United States of America

Hongxiang Hu

Affiliation Department of Integrative Biology and Pharmacology, The University of Texas Health Science Center at Houston, Houston, TX, 77030, United States of America

Michael B. Butterworth

Affiliation Department of Cell Biology, University of Pittsburgh School of Medicine, Pittsburgh, PA, 15261, United States of America

Jin-Bin Tian

Affiliation Department of Integrative Biology and Pharmacology, The University of Texas Health Science Center at Houston, Houston, TX, 77030, United States of America

Michael X. Zhu

Affiliation Department of Integrative Biology and Pharmacology, The University of Texas Health Science Center at Houston, Houston, TX, 77030, United States of America

Roger G. O’Neil

roger.g.oneil@uth.tmc.edu

Affiliation Department of Integrative Biology and Pharmacology, The University of Texas Health Science Center at Houston, Houston, TX, 77030, United States of America

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: RGO YL MBB JBT MXZ. Performed the experiments: YL HH RGO JBT. Analyzed the data: YL HH RGO JBT. Contributed reagents/materials/analysis tools: MBB RGO JBT MXZ. Wrote the paper: RGO YL MBB JBT MXZ.