About the Authors

Wenlin Li

Affiliation Department of Biochemistry and Department of Biophysics, University of Texas Southwestern Medical Center, Dallas, Texas, 75390–9050, United States of America

R. Dustin Schaeffer

Affiliation Howard Hughes Medical Institute, University of Texas Southwestern Medical Center, Dallas, Texas, 75390–9050, United States of America

Zbyszek Otwinowski

Affiliation Department of Biochemistry and Department of Biophysics, University of Texas Southwestern Medical Center, Dallas, Texas, 75390–9050, United States of America

Nick V. Grishin

grishin@chop.swmed.edu

Affiliations Howard Hughes Medical Institute, University of Texas Southwestern Medical Center, Dallas, Texas, 75390–9050, United States of America, Department of Biochemistry and Department of Biophysics, University of Texas Southwestern Medical Center, Dallas, Texas, 75390–9050, United States of America

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: WL ZO NG. Performed the experiments: WL. Analyzed the data: WL. Contributed reagents/materials/analysis tools: WL RS ZO NG. Wrote the paper: WL RS. Remade all figures: RS WL.