Two Arginine Residues of Streptococcus gordonii Sialic Acid-Binding Adhesin Hsa Are Essential for Interaction to Host Cell Receptors

Yumiko Urano-Tashiro; Yukihiro Takahashi; Riyo Oguchi; Kiyoshi Konishi

doi:10.1371/journal.pone.0154098

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Peer-reviewed

Research Article

Two Arginine Residues of Streptococcus gordonii Sialic Acid-Binding Adhesin Hsa Are Essential for Interaction to Host Cell Receptors

Yumiko Urano-Tashiro ,

* E-mail: yumiurano@tky.ndu.ac.jp

Affiliation Department of Microbiology, Nippon Dental University School of Life Dentistry at Tokyo, Fujimi, Chiyoda-ku, Tokyo, Japan
⨯
Yukihiro Takahashi,

Affiliation Department of Microbiology, Nippon Dental University School of Life Dentistry at Tokyo, Fujimi, Chiyoda-ku, Tokyo, Japan
⨯
Riyo Oguchi,

Affiliation Department of Pediatric Dentistry2, Nippon Dental University School of Life Dentistry at Tokyo, Fujimi, Chiyoda-ku, Tokyo, Japan
⨯
Kiyoshi Konishi

Affiliation Department of Microbiology, Nippon Dental University School of Life Dentistry at Tokyo, Fujimi, Chiyoda-ku, Tokyo, Japan
⨯

Two Arginine Residues of Streptococcus gordonii Sialic Acid-Binding Adhesin Hsa Are Essential for Interaction to Host Cell Receptors

Yumiko Urano-Tashiro,
Yukihiro Takahashi,
Riyo Oguchi,
Kiyoshi Konishi

Published: April 21, 2016
https://doi.org/10.1371/journal.pone.0154098

About the Authors

Yumiko Urano-Tashiro

* E-mail: yumiurano@tky.ndu.ac.jp

Affiliation Department of Microbiology, Nippon Dental University School of Life Dentistry at Tokyo, Fujimi, Chiyoda-ku, Tokyo, Japan

Yukihiro Takahashi

Affiliation Department of Microbiology, Nippon Dental University School of Life Dentistry at Tokyo, Fujimi, Chiyoda-ku, Tokyo, Japan

Riyo Oguchi

Affiliation Department of Pediatric Dentistry2, Nippon Dental University School of Life Dentistry at Tokyo, Fujimi, Chiyoda-ku, Tokyo, Japan

Kiyoshi Konishi

Affiliation Department of Microbiology, Nippon Dental University School of Life Dentistry at Tokyo, Fujimi, Chiyoda-ku, Tokyo, Japan

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: YU-T YT KK. Performed the experiments: YU-T YT. Analyzed the data: YU-T YT RO KK. Contributed reagents/materials/analysis tools: YT RO. Wrote the paper: YU-T YT.

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Red blood cells
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Sialic acids
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Platelet aggregation
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Glycoproteins
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White blood cells
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Host cells
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Hemagglutination
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Platelets
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