A Teleost Bactericidal Permeability-Increasing Protein Kills Gram-Negative Bacteria, Modulates Innate Immune Response, and Enhances Resistance against Bacterial and Viral Infection

Yuan-yuan Sun; Li Sun

doi:10.1371/journal.pone.0154045

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Open Access

Peer-reviewed

Research Article

A Teleost Bactericidal Permeability-Increasing Protein Kills Gram-Negative Bacteria, Modulates Innate Immune Response, and Enhances Resistance against Bacterial and Viral Infection

Yuan-yuan Sun,

Affiliations Key Laboratory of Experimental Marine Biology, Institute of Oceanology, Chinese Academy of Sciences, Qingdao, China, Laboratory for Marine Biology and Biotechnology, Qingdao National Laboratory for Marine Science and Technology, Qingdao, China, University of Chinese Academy of Sciences, Beijing, China
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Li Sun

* E-mail: lsun@qdio.ac.cn

Affiliations Key Laboratory of Experimental Marine Biology, Institute of Oceanology, Chinese Academy of Sciences, Qingdao, China, Laboratory for Marine Biology and Biotechnology, Qingdao National Laboratory for Marine Science and Technology, Qingdao, China
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A Teleost Bactericidal Permeability-Increasing Protein Kills Gram-Negative Bacteria, Modulates Innate Immune Response, and Enhances Resistance against Bacterial and Viral Infection

Yuan-yuan Sun,
Li Sun

Published: April 22, 2016
https://doi.org/10.1371/journal.pone.0154045

About the Authors

Yuan-yuan Sun

Affiliations Key Laboratory of Experimental Marine Biology, Institute of Oceanology, Chinese Academy of Sciences, Qingdao, China, Laboratory for Marine Biology and Biotechnology, Qingdao National Laboratory for Marine Science and Technology, Qingdao, China, University of Chinese Academy of Sciences, Beijing, China

Li Sun

* E-mail: lsun@qdio.ac.cn

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: LS YYS. Performed the experiments: YYS. Analyzed the data: YYS. Wrote the paper: LS.

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Pseudomonas fluorescens
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Bacteria
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Tongue
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Kidneys
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Gram negative bacteria
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Spleen
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Phagocytosis
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Viral transmission and infection
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