About the Authors

Christine M. Martin

Affiliation SAAD Centre for Pharmacy and Diabetes, Biomedical Sciences Research Institute, University of Ulster, Coleraine, Northern Ireland, United Kingdom

Vadivel Parthsarathy

Affiliation SAAD Centre for Pharmacy and Diabetes, Biomedical Sciences Research Institute, University of Ulster, Coleraine, Northern Ireland, United Kingdom

Annie Hasib

Affiliation SAAD Centre for Pharmacy and Diabetes, Biomedical Sciences Research Institute, University of Ulster, Coleraine, Northern Ireland, United Kingdom

Ming T. Ng

Affiliation SAAD Centre for Pharmacy and Diabetes, Biomedical Sciences Research Institute, University of Ulster, Coleraine, Northern Ireland, United Kingdom

Stephen McClean

Affiliation SAAD Centre for Pharmacy and Diabetes, Biomedical Sciences Research Institute, University of Ulster, Coleraine, Northern Ireland, United Kingdom

Peter R. Flatt

Affiliation SAAD Centre for Pharmacy and Diabetes, Biomedical Sciences Research Institute, University of Ulster, Coleraine, Northern Ireland, United Kingdom

Victor A. Gault

Affiliation SAAD Centre for Pharmacy and Diabetes, Biomedical Sciences Research Institute, University of Ulster, Coleraine, Northern Ireland, United Kingdom

Nigel Irwin

n.irwin@ulster.ac.uk

Affiliation SAAD Centre for Pharmacy and Diabetes, Biomedical Sciences Research Institute, University of Ulster, Coleraine, Northern Ireland, United Kingdom

Competing Interests

VAG, PRF and NI hold the following patent (European Patent Application No. 13700347.1 and US Serial No. 14/371878) entitled: ‘Peptides and peptide derivatives based on xenin’ claiming priority from International (PCT) Patent Application No. PCT/GB2013/050069 (WO2013/104929 A1) filed on Jan 14, 2013. The patent applications cover the use of stable xenin analogues for the treatment of metabolic disease including type 2 diabetes and obesity. This does not alter the authors' adherence to PLOS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: VAG SM PRF NI. Performed the experiments: CMM AH MTN VP. Analyzed the data: CMM AH MTN VP SM. Contributed reagents/materials/analysis tools: VAG CMM AH MTN VP SM PRF NI. Wrote the paper: VAG PRF NI.