About the Authors

Mireille A. Boink

Affiliations Department of Oral Biochemistry, Academic Centre for Dentistry Amsterdam (ACTA), University of Amsterdam and VU University Amsterdam, Amsterdam, The Netherlands, Department of Dermatology, VU University medical center, Amsterdam, The Netherlands

Sanne Roffel

Affiliations Department of Oral Biochemistry, Academic Centre for Dentistry Amsterdam (ACTA), University of Amsterdam and VU University Amsterdam, Amsterdam, The Netherlands, Department of Dermatology, VU University medical center, Amsterdam, The Netherlands

Kamran Nazmi

Affiliation Department of Oral Biochemistry, Academic Centre for Dentistry Amsterdam (ACTA), University of Amsterdam and VU University Amsterdam, Amsterdam, The Netherlands

Catherine van Montfrans

Affiliation Department of Dermatology, VU University medical center, Amsterdam, The Netherlands

Jan G. M. Bolscher

Affiliation Department of Oral Biochemistry, Academic Centre for Dentistry Amsterdam (ACTA), University of Amsterdam and VU University Amsterdam, Amsterdam, The Netherlands

Amit Gefen

Affiliation Department of Biomedical Engineering, Faculty of Engineering, Tel Aviv University, Tel Aviv, Israel

Enno C. I. Veerman

Affiliation Department of Oral Biochemistry, Academic Centre for Dentistry Amsterdam (ACTA), University of Amsterdam and VU University Amsterdam, Amsterdam, The Netherlands

Susan Gibbs

s.gibbs@acta.nl

Affiliations Department of Dermatology, VU University medical center, Amsterdam, The Netherlands, Department of Oral Cell Biology, Academic Centre for Dentistry Amsterdam (ACTA), University of Amsterdam and VU University, MOVE Research Institute Amsterdam, Amsterdam, The Netherlands

Competing Interests

The authors have the following interests: This study received funding from A-Skin BV. SG is cofounder of A-Skin BV which is a VU university medical centre start up company (SME). The authors have no patents, products in development or marketed products to declare which are relevant to this study. This does not alter the authors' adherence to all the PLOS ONE policies on sharing data and materials, as detailed online in the guide for authors.

Author Contributions

Conceived and designed the experiments: MAB SR JGMB ECIV SG. Performed the experiments: MAB SR. Analyzed the data: MAB SR JGMB ECIV SG. Contributed reagents/materials/analysis tools: KN AG. Wrote the paper: MAB CVM JGMB ECIV SG. Designed the software used in analysis: AG.