About the Authors

Robert J. Cardnell

Contributed equally to this work with: Robert J. Cardnell, Ying Feng

Affiliation Department of Thoracic/Head and Neck Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas, United States of America

Ying Feng

Contributed equally to this work with: Robert J. Cardnell, Ying Feng

Affiliation Biomarin Pharmaceutical Inc., Novato, California, United States of America

Seema Mukherjee

Affiliation Department of Thoracic/Head and Neck Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas, United States of America

Lixia Diao

Affiliation Departmant of Bioinformatics and Computational Biology, The University of Texas MD Anderson Cancer Center, Houston, Texas, United States of America

Pan Tong

Affiliation Departmant of Bioinformatics and Computational Biology, The University of Texas MD Anderson Cancer Center, Houston, Texas, United States of America

C. Allison Stewart

Affiliation Department of Thoracic/Head and Neck Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas, United States of America

Fatemeh Masrorpour

Affiliation Department of Thoracic/Head and Neck Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas, United States of America

YouHong Fan

Affiliation Department of Thoracic/Head and Neck Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas, United States of America

Monique Nilsson

Affiliation Department of Thoracic/Head and Neck Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas, United States of America

Yuqiao Shen

Affiliation Biomarin Pharmaceutical Inc., Novato, California, United States of America

John V. Heymach

Affiliation Department of Thoracic/Head and Neck Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas, United States of America

Jing Wang

Affiliation Departmant of Bioinformatics and Computational Biology, The University of Texas MD Anderson Cancer Center, Houston, Texas, United States of America

Lauren A. Byers

lbyers@mdanderson.org

Affiliation Department of Thoracic/Head and Neck Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas, United States of America

Competing Interests

YF and YS are employees of BioMarin Pharmaceutical Inc. JVH serves on the advisory boards of AstraZenica, AbbVie, Novartis and Genentech. This does not alter our adherence to PLOS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: RJC YF YS LAB. Performed the experiments: RJC YF SM CAS FM YHF MN. Analyzed the data: LD PT JW RJC JVH LAB YF YS. Contributed reagents/materials/analysis tools: PT JVH JW LAB YHF YS. Wrote the paper: RJC LAB.