About the Authors
- Elena-Raluca Nicoli
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Contributed equally to this work with: Elena-Raluca Nicoli, Nada Al Eisa, Celine V. M. Cluzeau
Affiliation Department of Pharmacology, University of Oxford, Oxford, United Kingdom
- Nada Al Eisa
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Contributed equally to this work with: Elena-Raluca Nicoli, Nada Al Eisa, Celine V. M. Cluzeau
Affiliation Department of Pharmacology, University of Oxford, Oxford, United Kingdom
- Celine V. M. Cluzeau
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Contributed equally to this work with: Elena-Raluca Nicoli, Nada Al Eisa, Celine V. M. Cluzeau
Affiliation Section of Molecular Dysmorphology, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Department of Health and Human Services, Bethesda, Maryland, United States of America
- Christopher A. Wassif
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Affiliations Department of Pharmacology, University of Oxford, Oxford, United Kingdom, Section of Molecular Dysmorphology, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Department of Health and Human Services, Bethesda, Maryland, United States of America
- James Gray
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Affiliation Department of Pharmacology, University of Oxford, Oxford, United Kingdom
- Kathryn R. Burkert
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Affiliation Section of Molecular Dysmorphology, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Department of Health and Human Services, Bethesda, Maryland, United States of America
- David A. Smith
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Affiliation Department of Pharmacology, University of Oxford, Oxford, United Kingdom
- Lauren Morris
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Affiliation Department of Pharmacology, University of Oxford, Oxford, United Kingdom
- Stephanie M. Cologna
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Affiliation Section of Molecular Dysmorphology, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Department of Health and Human Services, Bethesda, Maryland, United States of America
- Cody J. Peer
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Affiliation Clinical Pharmacology Program, Medical Oncology Branch, National Cancer Institute, Department of Health and Human Services, Bethesda, Maryland, United States of America
- Tristan M. Sissung
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Affiliation Clinical Pharmacology Program, Medical Oncology Branch, National Cancer Institute, Department of Health and Human Services, Bethesda, Maryland, United States of America
- Constantin-Daniel Uscatu
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Affiliations Department of Pharmacology, University of Oxford, Oxford, United Kingdom, Department of Cellular and Molecular Biology, University of Medicine and Pharmacy of Craiova, Craiova, Romania
- William D. Figg
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Affiliation Clinical Pharmacology Program, Medical Oncology Branch, National Cancer Institute, Department of Health and Human Services, Bethesda, Maryland, United States of America
- William J. Pavan
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Affiliation Genetic Disease Research Branch, National Human Genome Research Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, Maryland, United States of America
- Charles H. Vite
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Affiliation School of Veterinary Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America
- Forbes D. Porter
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* E-mail: Frances.platt@pharm.ox.ac.uk (FMP); fdporter@mail.nih.gov (FDP)
Affiliation Section of Molecular Dysmorphology, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Department of Health and Human Services, Bethesda, Maryland, United States of America
- Frances M. Platt
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* E-mail: Frances.platt@pharm.ox.ac.uk (FMP); fdporter@mail.nih.gov (FDP)
Affiliation Department of Pharmacology, University of Oxford, Oxford, United Kingdom
Competing Interests
The authors have declared that no competing interests exist.
Author Contributions
Conceived and designed the experiments: ERN NA CVMC CAW WDF CHV FDP FMP. Performed the experiments: ERN NA CVMC CAW JG KRB DAS SMC CJP TMS CDU WJP CHV. Analyzed the data: ERN NA CVMC CAW JG SMC CJP TMS CDU WDF WJP CHV FDP FMP. Contributed reagents/materials/analysis tools: WDF WJP CHV FDP FMP. Wrote the paper: ERN NA CVMC CAW SMC WDF WJP CHV FDP FMP. Relevant mouse studies were conducted: DAS LM.