Monitoring Solution Structures of Peroxisome Proliferator-Activated Receptor β/δ upon Ligand Binding

Rico Schwarz; Dirk Tänzler; Christian H. Ihling; Andrea Sinz

doi:10.1371/journal.pone.0151412

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Open Access

Peer-reviewed

Research Article

Monitoring Solution Structures of Peroxisome Proliferator-Activated Receptor β/δ upon Ligand Binding

Rico Schwarz,

Affiliation Department of Pharmaceutical Chemistry and Bioanalytics, Institute of Pharmacy, Martin Luther University Halle-Wittenberg, D-06120, Halle/Saale, Germany
⨯
Dirk Tänzler,

Affiliation Department of Pharmaceutical Chemistry and Bioanalytics, Institute of Pharmacy, Martin Luther University Halle-Wittenberg, D-06120, Halle/Saale, Germany
⨯
Christian H. Ihling,

Affiliation Department of Pharmaceutical Chemistry and Bioanalytics, Institute of Pharmacy, Martin Luther University Halle-Wittenberg, D-06120, Halle/Saale, Germany
⨯
Andrea Sinz

* E-mail: andrea.sinz@pharmazie.uni-halle.de

Affiliation Department of Pharmaceutical Chemistry and Bioanalytics, Institute of Pharmacy, Martin Luther University Halle-Wittenberg, D-06120, Halle/Saale, Germany
⨯

Monitoring Solution Structures of Peroxisome Proliferator-Activated Receptor β/δ upon Ligand Binding

Rico Schwarz,
Dirk Tänzler,
Christian H. Ihling,
Andrea Sinz

Published: March 18, 2016
https://doi.org/10.1371/journal.pone.0151412

About the Authors

Rico Schwarz

Affiliation Department of Pharmaceutical Chemistry and Bioanalytics, Institute of Pharmacy, Martin Luther University Halle-Wittenberg, D-06120, Halle/Saale, Germany

Dirk Tänzler

Affiliation Department of Pharmaceutical Chemistry and Bioanalytics, Institute of Pharmacy, Martin Luther University Halle-Wittenberg, D-06120, Halle/Saale, Germany

Christian H. Ihling

Affiliation Department of Pharmaceutical Chemistry and Bioanalytics, Institute of Pharmacy, Martin Luther University Halle-Wittenberg, D-06120, Halle/Saale, Germany

Andrea Sinz

* E-mail: andrea.sinz@pharmazie.uni-halle.de

Affiliation Department of Pharmaceutical Chemistry and Bioanalytics, Institute of Pharmacy, Martin Luther University Halle-Wittenberg, D-06120, Halle/Saale, Germany

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: RS AS. Performed the experiments: RS DT. Analyzed the data: RS CHI. Contributed reagents/materials/analysis tools: CHI. Wrote the paper: RS AS.

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Cross-linking
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Crystal structure
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Deamidation
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Fatty acids
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Germany
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Lysine
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Methionine
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Oxidation
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