About the Authors

Masahiro Terada

terada.masahiro@jikei.ac.jp

Affiliations Divison of Aerospace Medicine, The Jikei University School of Medicine, Minato-ku, Tokyo, Japan, Japan Aerospace Exploration Agency, Tsukuba City, Ibaraki, Japan, Space Biosciences Division, NASA Ames Research Center, Moffett Field, California, United States of America

Masaya Seki

Affiliation Advanced Engineering Services Co., Ltd., Takezono, Tsukuba City, Ibaraki, Japan

Rika Takahashi

Affiliation Advanced Engineering Services Co., Ltd., Takezono, Tsukuba City, Ibaraki, Japan

Shin Yamada

Affiliation Japan Aerospace Exploration Agency, Tsukuba City, Ibaraki, Japan

Akira Higashibata

Affiliations Japan Aerospace Exploration Agency, Tsukuba City, Ibaraki, Japan, Graduate School of Medical and Dental Sciences, Kagoshima University, Kagoshima City, Kagoshima, Japan

Hideyuki J. Majima

Affiliation Graduate School of Medical and Dental Sciences, Kagoshima University, Kagoshima City, Kagoshima, Japan

Masamichi Sudoh

Affiliations Divison of Aerospace Medicine, The Jikei University School of Medicine, Minato-ku, Tokyo, Japan, Japan Aerospace Exploration Agency, Tsukuba City, Ibaraki, Japan

Chiaki Mukai

Affiliation Japan Aerospace Exploration Agency, Tsukuba City, Ibaraki, Japan

Noriaki Ishioka

Affiliations Japan Aerospace Exploration Agency, Tsukuba City, Ibaraki, Japan, Graduate School of Medical and Dental Sciences, Kagoshima University, Kagoshima City, Kagoshima, Japan, Institute of Space and Astronautical Science, Sagamihara, Kanagawa, Japan, Department of Space and Astronautical Science, School of Physical Sciences, SOKENDAI (The Graduate University for Advanced Studies), Sagamihara, Kanagawa, Japan

Competing Interests

The experimental cost for this study was funded by Japan Aerospace Exploration Agency (JAXA). Masaya Seki and Rika Takahashi are employed by Advanced Engineering Services Co., Ltd. There are no patents, products in development, or marketed products to declare. This does not alter the authors’ adherence to all the PLOS ONE policies on sharing data and materials, as detailed online in the guide for authors.

Author Contributions

Conceived and designed the experiments: MT SY AH HM M. Sudoh CM NI. Performed the experiments: MT M. Seki RT. Analyzed the data: MT. Contributed reagents/materials/analysis tools: MT. Wrote the paper: MT.