About the Authors

Sarah O’Connell

soconnell@stjames.ie

Affiliation Department of Genito-Urinary Medicine and Infectious Disease, St James’s Hospital, Dublin, Ireland

Darren Lillis

Affiliation Emergency Medicine Department, St James’s Hospital, Dublin, Ireland

Aoife Cotter

Affiliation Department of Genito-Urinary Medicine and Infectious Disease, St James’s Hospital, Dublin, Ireland

Siobhan O’Dea

Affiliation Department of Genito-Urinary Medicine and Infectious Disease, St James’s Hospital, Dublin, Ireland

Helen Tuite

Affiliation Infectious Diseases Department, Galway University Hospital, Dublin, Ireland

Catherine Fleming

Affiliation Infectious Diseases Department, Galway University Hospital, Dublin, Ireland

Brendan Crowley

Affiliation Microbiology Department, St James’s Hospital, Dublin, Ireland

Ian Fitzgerald

Affiliation Microbiology Department, St James’s Hospital, Dublin, Ireland

Linda Dalby

Affiliation Microbiology Department, St James’s Hospital, Dublin, Ireland

Helen Barry

Affiliation Microbiology Department, St James’s Hospital, Dublin, Ireland

Darragh Shields

Affiliation Emergency Medicine Department, St James’s Hospital, Dublin, Ireland

Suzanne Norris

Affiliations Hepatology Department, St James’s Hospital, Dublin, Ireland, Department of Clinical Medicine, Trinity College Dublin, Dublin, Ireland

Patrick K. Plunkett

Affiliation Emergency Medicine Department, St James’s Hospital, Dublin, Ireland

Colm Bergin

Affiliations Department of Genito-Urinary Medicine and Infectious Disease, St James’s Hospital, Dublin, Ireland, Department of Clinical Medicine, Trinity College Dublin, Dublin, Ireland

Competing Interests

The authors received funding to complete the research from MSD pharmaceuticals, Gilead and GlaxoSmithKline. The funders had no role in study design, data collection and analysis, decision to publish or preparation of the manuscript. This funding has not contributed towards employment, consultancy and is not associated with any patents or products in development or otherwise. There are no restrictions imposed on sharing of data or materials, and this does not alter the authors’ adherence to PLOS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: SOC HT CF CB SOD SN PKP. Performed the experiments: DL DS LD IF HB BC. Analyzed the data: SOC AC. Contributed reagents/materials/analysis tools: LD HB IF. Wrote the paper: SOC. Reported results to the study team: BC.