About the Authors
- Igor Erjavec
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Contributed equally to this work with: Igor Erjavec, Tatjana Bordukalo-Niksic
Affiliation Laboratory of Mineralized Tissues, Center for Translational and Clinical Research, School of Medicine, University of Zagreb, Zagreb, Croatia
- Tatjana Bordukalo-Niksic
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Contributed equally to this work with: Igor Erjavec, Tatjana Bordukalo-Niksic
Affiliation Laboratory of Mineralized Tissues, Center for Translational and Clinical Research, School of Medicine, University of Zagreb, Zagreb, Croatia
- Jelena Brkljacic
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Affiliation Laboratory of Mineralized Tissues, Center for Translational and Clinical Research, School of Medicine, University of Zagreb, Zagreb, Croatia
- Danka Grcevic
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Affiliation Department of Physiology and Immunology, School of Medicine, University of Zagreb, Zagreb, Croatia
- Gordana Mokrovic
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Affiliation Laboratory for Neurochemistry and Molecular Neurobiology, Molecular Biology Department, Rudjer Boskovic Institute, Zagreb, Croatia
- Maja Kesic
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Affiliation Laboratory for Neurochemistry and Molecular Neurobiology, Molecular Biology Department, Rudjer Boskovic Institute, Zagreb, Croatia
- Dunja Rogic
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Affiliation Clinical Hospital Center Zagreb, Zagreb, Croatia
- William Zavadoski
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Affiliation Karos Pharmaceuticals, New Haven, CT, United States of America
- Vishwas M. Paralkar
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Affiliation Karos Pharmaceuticals, New Haven, CT, United States of America
- Lovorka Grgurevic
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Affiliation Laboratory of Mineralized Tissues, Center for Translational and Clinical Research, School of Medicine, University of Zagreb, Zagreb, Croatia
- Vladimir Trkulja
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Affiliation Department of Pharmacology, School of Medicine, University of Zagreb, Zagreb, Croatia
- Lipa Cicin-Sain
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Affiliation Laboratory for Neurochemistry and Molecular Neurobiology, Molecular Biology Department, Rudjer Boskovic Institute, Zagreb, Croatia
- Slobodan Vukicevic
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* E-mail: vukicev@mef.hr
Affiliation Laboratory of Mineralized Tissues, Center for Translational and Clinical Research, School of Medicine, University of Zagreb, Zagreb, Croatia
Competing Interests
I have read the journal's policy and the authors of this manuscript have the following competing interests: WZ and VMP are employees of Karos Pharmaceuticals which supplied the research with compound LX1032, which is a TPH1 specific inhibitor, and performed HPLC analyses. There are no patents, products in development or marketed products to declare. This does not alter the authors’ adherence to all the PLOS ONE policies on sharing data and materials, as detailed online in the guide for authors.
Author Contributions
Conceived and designed the experiments: IE TBN LCS SV. Performed the experiments: IE TBN JB GM MK WZ. Analyzed the data: IE TBN VT LG LCS. Contributed reagents/materials/analysis tools: DG WZ DR VMP. Wrote the paper: IE TBN VMP LG VT SV.