About the Authors

W. Edward Visser

w.e.visser@erasmusmc.nl

Affiliation Dept of Internal Medicine, Erasmus Medical Center, Rotterdam, The Netherlands

Cíntia R. Bombardieri

Contributed equally to this work with: Cíntia R. Bombardieri, Chantal Zevenbergen

Affiliation MGC Dept of Genetics, Cancer Genomics Center, Erasmus Medical Center, Rotterdam, The Netherlands

Chantal Zevenbergen

Contributed equally to this work with: Cíntia R. Bombardieri, Chantal Zevenbergen

Affiliation Dept of Internal Medicine, Erasmus Medical Center, Rotterdam, The Netherlands

Sander Barnhoorn

Affiliation MGC Dept of Genetics, Cancer Genomics Center, Erasmus Medical Center, Rotterdam, The Netherlands

Alexandre Ottaviani

Affiliations MGC Dept of Genetics, Cancer Genomics Center, Erasmus Medical Center, Rotterdam, The Netherlands, Institute for Research on Cancer and Aging, Nice (IRCAN), UMR 7284 CNRS U1081 INSERM UNS, 28 avenue de Valombrose Faculté de Médecine, Nice, France

Ingrid van der Pluijm

Current address: Dept of Vascular Surgery, Erasmus Medical Center, Rotterdam, The Netherlands

Affiliation MGC Dept of Genetics, Cancer Genomics Center, Erasmus Medical Center, Rotterdam, The Netherlands

Renata Brandt

Affiliation MGC Dept of Genetics, Cancer Genomics Center, Erasmus Medical Center, Rotterdam, The Netherlands

Ellen Kaptein

Affiliation Dept of Internal Medicine, Erasmus Medical Center, Rotterdam, The Netherlands

Ramona van Heerebeek

Affiliation Dept of Internal Medicine, Erasmus Medical Center, Rotterdam, The Netherlands

Hans van Toor

Affiliation Dept of Internal Medicine, Erasmus Medical Center, Rotterdam, The Netherlands

George A. Garinis

Current address: FORTH, Institute of Molecular Biology and Biotechnology, Heraklion, Crete, Greece

Affiliation MGC Dept of Genetics, Cancer Genomics Center, Erasmus Medical Center, Rotterdam, The Netherlands

Robin P. Peeters

Affiliation Dept of Internal Medicine, Erasmus Medical Center, Rotterdam, The Netherlands

Marco Medici

Affiliation Dept of Internal Medicine, Erasmus Medical Center, Rotterdam, The Netherlands

Willy van Ham

Affiliation Laboratory of Comparative Endocrinology, Biology Department, KULeuven, Leuven, Belgium

Wilbert P. Vermeij

Affiliation MGC Dept of Genetics, Cancer Genomics Center, Erasmus Medical Center, Rotterdam, The Netherlands

Monique C. de Waard

Current address: Dept of intensive Care, VU Medical Center, Amsterdam, The Netherlands

Affiliation MGC Dept of Genetics, Cancer Genomics Center, Erasmus Medical Center, Rotterdam, The Netherlands

Ronald R. de Krijger

Current address: Dept. of Pathology, Reinier de Graaf Gasthuis, Delft, The Netherlands

Affiliation Dept of Pathology, Erasmus Medical Center, Rotterdam, The Netherlands

Anita Boelen

Affiliation Dept of Endocrinology and Metabolism, Academic Medical Center, Amsterdam, The Netherlands

Joan Kwakkel

Affiliation Dept of Endocrinology and Metabolism, Academic Medical Center, Amsterdam, The Netherlands

John J. Kopchick

Affiliation Dept of Biomedical Sciences, Edison Biotechnology Institute, Ohio University, Athens, Ohio, United States of America

Edward O. List

Affiliation Dept of Biomedical Sciences, Edison Biotechnology Institute, Ohio University, Athens, Ohio, United States of America

Joost P. M. Melis

Affiliation Dept of Toxicogenetics, Leiden University Medical Center, Leiden, The Netherlands

Veerle M. Darras

Affiliation Laboratory of Comparative Endocrinology, Biology Department, KULeuven, Leuven, Belgium

Martijn E. T. Dollé

Affiliation Centre for Health Protection Research, National Institute of Public Health and the Environment (RIVM), Bilthoven, The Netherlands

Gijsbertus T. J. van der Horst

Affiliation MGC Dept of Genetics, Cancer Genomics Center, Erasmus Medical Center, Rotterdam, The Netherlands

Jan H. J. Hoeijmakers

Affiliation MGC Dept of Genetics, Cancer Genomics Center, Erasmus Medical Center, Rotterdam, The Netherlands

Theo J. Visser

Affiliation Dept of Internal Medicine, Erasmus Medical Center, Rotterdam, The Netherlands

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: WEV JHJH TJV. Performed the experiments: WEV CRB CZ AO EK RVH HVT WVH WPV MCDW JK. Analyzed the data: WEV RPP JHJH RRDK AB TJV. Contributed reagents/materials/analysis tools: IVDP RB GAG MM JJK EOL JPMM VMD METD GTJVDH SB. Wrote the paper: WEV JHJH TJV.