About the Authors
- Sara Costa-Cabral
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Affiliations The CRUK Gene Function Laboratory, The Institute of Cancer Research, London, SW3 6JB, United Kingdom, Breakthrough Breast Cancer Research Centre, The Institute of Cancer Research, London, SW3 6JB, United Kingdom
- Rachel Brough
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Affiliations The CRUK Gene Function Laboratory, The Institute of Cancer Research, London, SW3 6JB, United Kingdom, Breakthrough Breast Cancer Research Centre, The Institute of Cancer Research, London, SW3 6JB, United Kingdom
- Asha Konde
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Affiliations The CRUK Gene Function Laboratory, The Institute of Cancer Research, London, SW3 6JB, United Kingdom, Breakthrough Breast Cancer Research Centre, The Institute of Cancer Research, London, SW3 6JB, United Kingdom
- Marieke Aarts
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Affiliations The CRUK Gene Function Laboratory, The Institute of Cancer Research, London, SW3 6JB, United Kingdom, Breakthrough Breast Cancer Research Centre, The Institute of Cancer Research, London, SW3 6JB, United Kingdom
- James Campbell
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Affiliations The CRUK Gene Function Laboratory, The Institute of Cancer Research, London, SW3 6JB, United Kingdom, Breakthrough Breast Cancer Research Centre, The Institute of Cancer Research, London, SW3 6JB, United Kingdom
- Eliana Marinari
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Affiliations The CRUK Gene Function Laboratory, The Institute of Cancer Research, London, SW3 6JB, United Kingdom, Breakthrough Breast Cancer Research Centre, The Institute of Cancer Research, London, SW3 6JB, United Kingdom
- Jenna Riffell
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Affiliations The CRUK Gene Function Laboratory, The Institute of Cancer Research, London, SW3 6JB, United Kingdom, Breakthrough Breast Cancer Research Centre, The Institute of Cancer Research, London, SW3 6JB, United Kingdom
- Alberto Bardelli
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Affiliation IFOM—FIRC Institute of Molecular Oncology, Via Adamello 16, 20139, Milan, Italy
- Christopher Torrance
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Current address: PhoreMost, 23 Cambridge Science Park, Milton Road, Cambridge, CB4 0EY, United Kingdom
Affiliation Horizon Discovery, 7100 Cambridge Research Park, Waterbeach, Cambridge, CB25 9TL, United Kingdom
- Christopher J. Lord
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* E-mail: Chris.Lord@icr.ac.uk
Affiliations The CRUK Gene Function Laboratory, The Institute of Cancer Research, London, SW3 6JB, United Kingdom, Breakthrough Breast Cancer Research Centre, The Institute of Cancer Research, London, SW3 6JB, United Kingdom
- Alan Ashworth
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Current address: UCSF Helen Diller Family Comprehensive Cancer Center, University of California San Francisco, San Francisco, California, 94158, United States of America
Affiliations The CRUK Gene Function Laboratory, The Institute of Cancer Research, London, SW3 6JB, United Kingdom, Breakthrough Breast Cancer Research Centre, The Institute of Cancer Research, London, SW3 6JB, United Kingdom
Competing Interests
Horizon Discovery provided the KRAS isogenic cell lines. The authors state that this does not alter their adherence to PLOS ONE policies on sharing data and materials.
Author Contributions
Conceived and designed the experiments: SCC CJL AA MA JR. Performed the experiments: SCC RB AK EM. Analyzed the data: SCC JC. Contributed reagents/materials/analysis tools: AB CT. Wrote the paper: SCC CJL AA.