About the Authors

Saurabh Jain

Affiliation University of Edinburgh, Institute of Genetic and Molecular Medicine and School of Veterinary Medicine, Edinburgh, EH4 2XR, United Kingdom

Luca Aresu

Affiliation Dipartimento di Biomedicina Comparata e Alimentazione (BCA) Department of Comparative Biomedicine and Food Science, Università di Padova 35020 Legnaro (PD), Italy

Stefano Comazzi

Affiliation Dipartimento di Scienze Veterinarie e Sanità Pubblica, Università degli Studi di Milano, via Celoria 10, 20133 Milano, Italy

Jianguo Shi

Affiliation University of Edinburgh, Institute of Genetic and Molecular Medicine and School of Veterinary Medicine, Edinburgh, EH4 2XR, United Kingdom

Erin Worrall

Affiliation University of Edinburgh, Institute of Genetic and Molecular Medicine and School of Veterinary Medicine, Edinburgh, EH4 2XR, United Kingdom

John Clayton

Affiliation Mologic, Ltd, Bedford Technology Park, Thurleigh, Bedford, MK44 2YP, United Kingdom

William Humphries

Affiliation Mologic, Ltd, Bedford Technology Park, Thurleigh, Bedford, MK44 2YP, United Kingdom

Sandra Hemmington

Affiliation Mologic, Ltd, Bedford Technology Park, Thurleigh, Bedford, MK44 2YP, United Kingdom

Paul Davis

Affiliation Mologic, Ltd, Bedford Technology Park, Thurleigh, Bedford, MK44 2YP, United Kingdom

Euan Murray

Affiliations University of Edinburgh, Institute of Genetic and Molecular Medicine and School of Veterinary Medicine, Edinburgh, EH4 2XR, United Kingdom, INSERM Unité 940, Institut de Génétique Moléculaire, Université Paris 7, Hôpital St Louis, 27 rue Juliette Dodu, Paris, France

Asmare A. Limeneh

Affiliation Bahit Dar University College of Medicine and Health Sciences Department of Medical Biochemistry and Molecular Biology, Bahir Dar, Ethiopia

Kathryn Ball

Affiliation University of Edinburgh, Institute of Genetic and Molecular Medicine and School of Veterinary Medicine, Edinburgh, EH4 2XR, United Kingdom

Eva Ruckova

Affiliation Regional Centre for Applied Molecular Oncology, Masaryk Memorial Cancer Institute, 656 53 Brno, Czech Republic

Petr Muller

Affiliation Regional Centre for Applied Molecular Oncology, Masaryk Memorial Cancer Institute, 656 53 Brno, Czech Republic

Borek Vojtesek

Affiliation Regional Centre for Applied Molecular Oncology, Masaryk Memorial Cancer Institute, 656 53 Brno, Czech Republic

Robin Fahraeus

Affiliation INSERM Unité 940, Institut de Génétique Moléculaire, Université Paris 7, Hôpital St Louis, 27 rue Juliette Dodu, Paris, France

David Argyle

Affiliation University of Edinburgh, Institute of Genetic and Molecular Medicine and School of Veterinary Medicine, Edinburgh, EH4 2XR, United Kingdom

Ted R. Hupp

Ted.Hupp@ed.ac.uk

Affiliation University of Edinburgh, Institute of Genetic and Molecular Medicine and School of Veterinary Medicine, Edinburgh, EH4 2XR, United Kingdom

Competing Interests

There are no competing interests in this project with Mologic. Mologic have not funded the project nor are they currently working on or have they worked on the CD20 project. There are no patents or products in development with this project with Mologic. Mologic scientists are co-authors as they have performed the Kd determination of the antibody (according to the methods sections using Octet Red). In addition, Mologic advised the Edinburgh authors on how to clone and use non-commercially sensitive CPG2 vectors for production of chimeric antibodies. Mologic as co-authors do not alter the authors' adherence to all PLOS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: SJ LA SC JS JC WH ER PM TH EW. Performed the experiments: SJ LA SC JS JC WH ER PM TH. Analyzed the data: SJ LA SC JS JC WH SH PD EM AL KB ER PM BV RF DA TH. Contributed reagents/materials/analysis tools: SJ LA SC JS JC ER PM DA TH. Wrote the paper: SJ LA SC JC JS AL KB DA TH.