About the Authors

Marina Padroni

Affiliation Section of Neurology, Department of Biological, Psychiatric and Psychological Science, University of Ferrara, Ferrara, Italy

Andrea Bernardoni

Affiliation Section of Diagnostic Imaging, Department of Morphology, Surgery and Experimental Medicine, University of Ferrara, Ferrara, Italy

Carmine Tamborino

Affiliation Section of Neurology, Department of Biological, Psychiatric and Psychological Science, University of Ferrara, Ferrara, Italy

Gloria Roversi

Affiliation Section of Neurology, Department of Biological, Psychiatric and Psychological Science, University of Ferrara, Ferrara, Italy

Massimo Borrelli

Affiliation Neuroradiology Unit, Department of Neuroscience and Rehabilitation, Azienda Ospedaliera Universitaria, Ferrara, Italy

Andrea Saletti

Affiliation Neuroradiology Unit, Department of Neuroscience and Rehabilitation, Azienda Ospedaliera Universitaria, Ferrara, Italy

Alessandro De Vito

Affiliation Neurology Unit, Department of Neuroscience and Rehabilitation, Azienda Ospedaliera Universitaria, Ferrara, Italy

Cristiano Azzini

Affiliation Neurology Unit, Department of Neuroscience and Rehabilitation, Azienda Ospedaliera Universitaria, Ferrara, Italy

Luca Borgatti

Affiliation Neuroradiology Unit, Department of Neuroscience and Rehabilitation, Azienda Ospedaliera Universitaria, Ferrara, Italy

Onofrio Marcello

Affiliation Neuroradiology Unit, Department of Neuroscience and Rehabilitation, Azienda Ospedaliera Universitaria, Ferrara, Italy

Christopher d’Esterre

Affiliations Calgary Stroke Program, Department of Clinical Neurosciences, University of Calgary, Calgary, Alberta, Canada, Imaging Research Lab, Robarts Research Institute, Western Ontario University, London, Ontario, Canada

Stefano Ceruti

Affiliation Neuroradiology Unit, Department of Neuroscience and Rehabilitation, Azienda Ospedaliera Universitaria, Ferrara, Italy

Ilaria Casetta

Affiliation Section of Neurology, Department of Biological, Psychiatric and Psychological Science, University of Ferrara, Ferrara, Italy

Ting-Yim Lee

Affiliations Imaging Research Lab, Robarts Research Institute, Western Ontario University, London, Ontario, Canada, Imaging program, Lawson Health Research Institute, Western Ontario University, London, Ontario, Canada

Enrico Fainardi

henryfai@tin.it

Affiliation Neuroradiology Unit, Department of Neuroscience and Rehabilitation, Azienda Ospedaliera Universitaria, Ferrara, Italy

Competing Interests

TYL licenses CT Perfusion software to and receives funding from GE Healthcare. This does not alter the authors’ adherence to PLOS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: MP EF. Performed the experiments: MP AB CT EF. Analyzed the data: MP EF. Contributed reagents/materials/analysis tools: GR MB AS AD CA LB OM SC IC. Wrote the paper: MP CD TYL EF.