About the Authors

Juho Pirhonen

juho.pirhonen@helsinki.fi

Affiliations Departments of Anatomy, Faculty of Medicine, University of Helsinki, Helsinki, Finland, Minerva Foundation Institute for Medical Research, Helsinki, Finland

Johanna Arola

Affiliations Department of Pathology, Faculty of Medicine, University of Helsinki, Helsinki, Finland, Department of Pathology, HUSLAB, Helsinki, Finland

Sanja Sädevirta

Affiliations Department of Medicine, Faculty of Medicine, University of Helsinki, Helsinki, Finland, Minerva Foundation Institute for Medical Research, Helsinki, Finland

Panu Luukkonen

Affiliations Department of Medicine, Faculty of Medicine, University of Helsinki, Helsinki, Finland, Minerva Foundation Institute for Medical Research, Helsinki, Finland

Sanna-Maria Karppinen

Affiliation Faculty of Biochemistry and Molecular Medicine, Oulu Center for Cell-Matrix Research, Biocenter Oulu, Oulu, Finland

Taina Pihlajaniemi

Affiliation Faculty of Biochemistry and Molecular Medicine, Oulu Center for Cell-Matrix Research, Biocenter Oulu, Oulu, Finland

Antti Isomäki

Affiliation Departments of Anatomy, Faculty of Medicine, University of Helsinki, Helsinki, Finland

Mika Hukkanen

Affiliation Departments of Anatomy, Faculty of Medicine, University of Helsinki, Helsinki, Finland

Hannele Yki-Järvinen

Contributed equally to this work with: Hannele Yki-Järvinen, Elina Ikonen

Affiliations Department of Medicine, Faculty of Medicine, University of Helsinki, Helsinki, Finland, Minerva Foundation Institute for Medical Research, Helsinki, Finland

Elina Ikonen

Contributed equally to this work with: Hannele Yki-Järvinen, Elina Ikonen

Affiliations Departments of Anatomy, Faculty of Medicine, University of Helsinki, Helsinki, Finland, Minerva Foundation Institute for Medical Research, Helsinki, Finland

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: EI HYJ. Performed the experiments: JP JA SMK MH AI. Analyzed the data: JP JA PL SMK TP. Contributed reagents/materials/analysis tools: EI HYJ TP SS. Wrote the paper: EI HYJ JP.