About the Authors

Xiangjing Gao

Affiliations Zhejiang Provincial Center for Disease Control and Prevention, Hangzhou, Zhejiang, 310051, China, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, The First Affiliated Hospital, Zhejiang University, Hangzhou, Zhejiang, 310003, China

Guanglin Zhang

Affiliation Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, The First Affiliated Hospital, Zhejiang University, Hangzhou, Zhejiang, 310003, China

Shigang Shan

Affiliation Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, The First Affiliated Hospital, Zhejiang University, Hangzhou, Zhejiang, 310003, China

Yunlong Shang

Affiliation Zhejiang CONBA Pharmaceutical Co. Ltd., Hangzhou, Zhejiang, 310058, China

Linfeng Chi

Affiliations Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, The First Affiliated Hospital, Zhejiang University, Hangzhou, Zhejiang, 310003, China, The Affiliated Stomatology Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, 310003, China

Hongjuan Li

Affiliation Department of Toxicology, Hangzhou Normal University School of Medicine, Hangzhou, Zhejiang, 310016, China

Yifei Cao

Affiliation Department of Toxicology, Hangzhou Normal University School of Medicine, Hangzhou, Zhejiang, 310016, China

Xinqiang Zhu

Affiliation Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, The First Affiliated Hospital, Zhejiang University, Hangzhou, Zhejiang, 310003, China

Meibian Zhang

mbzhang@cdc.zj.cn (MBZ); gastate@zju.edu.cn (JY)

Affiliation Zhejiang Provincial Center for Disease Control and Prevention, Hangzhou, Zhejiang, 310051, China

Jun Yang

mbzhang@cdc.zj.cn (MBZ); gastate@zju.edu.cn (JY)

Affiliations Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, The First Affiliated Hospital, Zhejiang University, Hangzhou, Zhejiang, 310003, China, Department of Toxicology, Hangzhou Normal University School of Medicine, Hangzhou, Zhejiang, 310016, China

Competing Interests

The authors have declared that no competing interests exist. Although one author is employed by a commercial company "Zhejiang CONBA Pharmaceutical Co. Ltd.", it does not alter the authors' adherence to PLOS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: XJG GLZ LFC. Performed the experiments: XJG SGS YLS GLZ. Analyzed the data: XJG SGS HJL YFC. Contributed reagents/materials/analysis tools: YLS MBZ JY. Wrote the paper: XQZ MBZ JY.