About the Authors

Claudia S. Priglinger

claudia.alge-priglinger@med.uni-muenchen.de

Affiliation Department of Ophthalmology, Ludwig-Maximilians-University, Munich, Germany

Jara Obermann

Affiliation Research Unit Protein Science, Helmholtz Zentrum Munich, German Research Center for Environmental Health (GmbH), Munich, Germany

Christoph M. Szober

Affiliation Department of Ophthalmology, Ludwig-Maximilians-University, Munich, Germany

Juliane Merl-Pham

Affiliation Research Unit Protein Science, Helmholtz Zentrum Munich, German Research Center for Environmental Health (GmbH), Munich, Germany

Uli Ohmayer

Affiliation Research Unit Protein Science, Helmholtz Zentrum Munich, German Research Center for Environmental Health (GmbH), Munich, Germany

Jennifer Behler

Affiliation Research Unit Protein Science, Helmholtz Zentrum Munich, German Research Center for Environmental Health (GmbH), Munich, Germany

Fabian Gruhn

Affiliation Research Unit Protein Science, Helmholtz Zentrum Munich, German Research Center for Environmental Health (GmbH), Munich, Germany

Thomas C. Kreutzer

Affiliation Department of Ophthalmology, Ludwig-Maximilians-University, Munich, Germany

Christian Wertheimer

Affiliation Department of Ophthalmology, Ludwig-Maximilians-University, Munich, Germany

Arie Geerlof

Affiliation Protein Expression and Purification Facility, Institute of Structural Biology, Helmholtz Zentrum Munich, German Research Center for Environmental Health (GmbH), Neuherberg, Germany

Siegfried G. Priglinger

Affiliation Department of Ophthalmology, Ludwig-Maximilians-University, Munich, Germany

Stefanie M. Hauck

Affiliation Research Unit Protein Science, Helmholtz Zentrum Munich, German Research Center for Environmental Health (GmbH), Munich, Germany

Competing Interests

This study was supported through a research grant from Novartis Pharma Germany (www.novartis.de). This does not alter the authors’ adherence to PLOS ONE policies on sharing data and materials. Novartis had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript; this was the sole responsibility of the authors. This study was financially supported by Novartis Pharma Germany. There are no employment, consultancy, patents, products in development or marketed products to declare.

Author Contributions

Conceived and designed the experiments: CSP SMH CS JO AG JMP UO. Performed the experiments: CSP JO CS JB FG SGP UO. Analyzed the data: CSP JO TK SMH SGP CW AG UO. Contributed reagents/materials/analysis tools: CSP SMH AG SGP. Wrote the paper: CSP SMH JO TK SGP.