Macrophage Migration Inhibitory Factor Secretion Is Induced by Ionizing Radiation and Oxidative Stress in Cancer Cells

Yashi Gupta; Vinay Pasupuleti; Weinan Du; Scott M. Welford

doi:10.1371/journal.pone.0146482

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Open Access

Peer-reviewed

Research Article

Macrophage Migration Inhibitory Factor Secretion Is Induced by Ionizing Radiation and Oxidative Stress in Cancer Cells

Yashi Gupta ,

Contributed equally to this work with: Yashi Gupta, Vinay Pasupuleti

Affiliations Department of Radiation Oncology, Case Western Reserve University, 10900 Euclid Avenue, Cleveland, Ohio, 44106, United States of America, Department of Biochemistry, Case Western Reserve University, 10900 Euclid Avenue, Cleveland, Ohio, 44106, United States of America
⨯
Vinay Pasupuleti ,

Contributed equally to this work with: Yashi Gupta, Vinay Pasupuleti

Affiliation Department of Radiation Oncology, Case Western Reserve University, 10900 Euclid Avenue, Cleveland, Ohio, 44106, United States of America
⨯
Weinan Du,

Affiliation Department of Radiation Oncology, Case Western Reserve University, 10900 Euclid Avenue, Cleveland, Ohio, 44106, United States of America
⨯
Scott M. Welford

* E-mail: scott.welford@case.edu

Affiliation Department of Radiation Oncology, Case Western Reserve University, 10900 Euclid Avenue, Cleveland, Ohio, 44106, United States of America
⨯

Macrophage Migration Inhibitory Factor Secretion Is Induced by Ionizing Radiation and Oxidative Stress in Cancer Cells

Yashi Gupta,
Vinay Pasupuleti,
Weinan Du,
Scott M. Welford

Published: January 7, 2016
https://doi.org/10.1371/journal.pone.0146482

About the Authors

Yashi Gupta

Contributed equally to this work with: Yashi Gupta, Vinay Pasupuleti

Affiliations Department of Radiation Oncology, Case Western Reserve University, 10900 Euclid Avenue, Cleveland, Ohio, 44106, United States of America, Department of Biochemistry, Case Western Reserve University, 10900 Euclid Avenue, Cleveland, Ohio, 44106, United States of America

Vinay Pasupuleti

Contributed equally to this work with: Yashi Gupta, Vinay Pasupuleti

Affiliation Department of Radiation Oncology, Case Western Reserve University, 10900 Euclid Avenue, Cleveland, Ohio, 44106, United States of America

Weinan Du

Affiliation Department of Radiation Oncology, Case Western Reserve University, 10900 Euclid Avenue, Cleveland, Ohio, 44106, United States of America

Scott M. Welford

* E-mail: scott.welford@case.edu

Affiliation Department of Radiation Oncology, Case Western Reserve University, 10900 Euclid Avenue, Cleveland, Ohio, 44106, United States of America

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: YG VP WD SMW. Performed the experiments: YG VP WD. Analyzed the data: YG VP WD SMW. Wrote the paper: YG VP SMW.

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Secretion
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Renal cancer
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Lung and intrathoracic tumors
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Breast cancer
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DNA damage
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Malignant tumors
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Cancer treatment
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Ionizing radiation
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