About the Authors
- Kirsty E. Russell
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Affiliation Airway Disease Section, National Heart & Lung Institute, NIHR Respiratory Biomedical Research Unit at the Royal Brompton NHS Foundation Trust and Imperial College London, London, United Kingdom
- Kian Fan Chung
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Affiliation Airway Disease Section, National Heart & Lung Institute, NIHR Respiratory Biomedical Research Unit at the Royal Brompton NHS Foundation Trust and Imperial College London, London, United Kingdom
- Colin J. Clarke
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Affiliation Airway Disease Section, National Heart & Lung Institute, NIHR Respiratory Biomedical Research Unit at the Royal Brompton NHS Foundation Trust and Imperial College London, London, United Kingdom
- Andrew L. Durham
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Affiliation Airway Disease Section, National Heart & Lung Institute, NIHR Respiratory Biomedical Research Unit at the Royal Brompton NHS Foundation Trust and Imperial College London, London, United Kingdom
- Patrick Mallia
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Affiliation Airway Disease Infection Section, National Heart & Lung Institute, Imperial College London, London, United Kingdom
- Joseph Footitt
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† Deceased.
Affiliation Airway Disease Infection Section, National Heart & Lung Institute, Imperial College London, London, United Kingdom
- Sebastian L. Johnston
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Affiliation Airway Disease Infection Section, National Heart & Lung Institute, Imperial College London, London, United Kingdom
- Peter J. Barnes
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Affiliation Airway Disease Section, National Heart & Lung Institute, NIHR Respiratory Biomedical Research Unit at the Royal Brompton NHS Foundation Trust and Imperial College London, London, United Kingdom
- Simon R. Hall
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Affiliation RRI DPU, GlaxoSmithKline, Stevenage, United Kingdom
- Karen D. Simpson
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Affiliation RRI DPU, GlaxoSmithKline, Stevenage, United Kingdom
- Malcolm R. Starkey
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Affiliation Priority Research Centre for Respiratory Diseases, Hunter Medical Research Institute and The University of Newcastle, Newcastle, Australia
- Philip M. Hansbro
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Affiliation Priority Research Centre for Respiratory Diseases, Hunter Medical Research Institute and The University of Newcastle, Newcastle, Australia
- Ian M. Adcock
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Affiliation Airway Disease Section, National Heart & Lung Institute, NIHR Respiratory Biomedical Research Unit at the Royal Brompton NHS Foundation Trust and Imperial College London, London, United Kingdom
- Coen H. Wiegman
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* E-mail: c.wiegman@imperial.ac.uk
Affiliation Airway Disease Section, National Heart & Lung Institute, NIHR Respiratory Biomedical Research Unit at the Royal Brompton NHS Foundation Trust and Imperial College London, London, United Kingdom
Competing Interests
SRH and KDS are employees of GSK. This study was funded in part by GSK and by the MRC-ABPI COPDMAP consortia. There are no patents, products in development or marketed products to declare. This does not alter the authors' adherence to all the PLOS ONE policies on sharing data and materials.
Author Contributions
Conceived and designed the experiments: KER KFC SLJ PJB SRH KDS IMA CHW. Performed the experiments: KER CC ALD CHW MRS PMH JF PM. Analyzed the data: KER CHW MRS SRH KDS. Wrote the paper: KER KFC IMA CHW SLJ.