About the Authors

Sebastian K. Wandinger

Contributed equally to this work with: Sebastian K. Wandinger, Idoya Lahortiga

Affiliation Evotec (München) GmbH, Martinsried, Germany

Idoya Lahortiga

Contributed equally to this work with: Sebastian K. Wandinger, Idoya Lahortiga

Affiliations VIB Center for the Biology of Disease, Leuven, Belgium, KU Leuven, Center for Human Genetics, Leuven, Belgium

Kris Jacobs

Affiliations VIB Center for the Biology of Disease, Leuven, Belgium, KU Leuven, Center for Human Genetics, Leuven, Belgium

Martin Klammer

Affiliation Evotec (München) GmbH, Martinsried, Germany

Nicole Jordan

Affiliation Evotec (München) GmbH, Martinsried, Germany

Sarah Elschenbroich

Affiliation Evotec (München) GmbH, Martinsried, Germany

Marc Parade

Affiliation Oncology Drug Discovery, Janssen Research & Development, Janssen Pharmaceutica NV, Beerse, Belgium

Edgar Jacoby

Affiliation Oncology Drug Discovery, Janssen Research & Development, Janssen Pharmaceutica NV, Beerse, Belgium

Joannes T. M. Linders

Affiliation Oncology Drug Discovery, Janssen Research & Development, Janssen Pharmaceutica NV, Beerse, Belgium

Dirk Brehmer

Affiliation Oncology Drug Discovery, Janssen Research & Development, Janssen Pharmaceutica NV, Beerse, Belgium

Jan Cools

jan.cools@cme.vib-kuleuven.be (JC); henrik.daub@evotec.com (HD)

Affiliations VIB Center for the Biology of Disease, Leuven, Belgium, KU Leuven, Center for Human Genetics, Leuven, Belgium

Henrik Daub

jan.cools@cme.vib-kuleuven.be (JC); henrik.daub@evotec.com (HD)

Affiliation Evotec (München) GmbH, Martinsried, Germany

Competing Interests

The authors have the following interests. Sebastian K. Wandinger, Martin Klammer, Nicole Jordan, Sarah Elschenbroich and Henrik Daub are employed by Evotec (München) GmbH, and Marc Parade, Edgar Jacoby, Joannes T.M. Linders and Dirk Brehmer by Janssen Pharmaceutica. This does not alter the authors’ adherence to PLOS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: SKW IL EJ DB JC HD. Performed the experiments: SKW IL KJ NJ SE MP EJ. Analyzed the data: SKW IL MK JTML JC HD. Wrote the paper: SKW IL DB JC HD.