About the Authors

Wendy M. McKimpson

Affiliations Department of Medicine (Cardiology), Albert Einstein College of Medicine, Bronx, NY 10461, United States of America, Department of Cell Biology, Albert Einstein College of Medicine, Bronx, NY 10461, United States of America, Wilf Family Cardiovascular Research Institute, Albert Einstein College of Medicine, Bronx, NY 10461, United States of America

Ziqiang Yuan

Affiliation Department of Surgery, Albert Einstein College of Medicine, Bronx, NY 10461, United States of America

Min Zheng

Affiliations Department of Medicine (Cardiology), Albert Einstein College of Medicine, Bronx, NY 10461, United States of America, Wilf Family Cardiovascular Research Institute, Albert Einstein College of Medicine, Bronx, NY 10461, United States of America

Judy S. Crabtree

Affiliation Department of Genetics, Louisiana State University Health Sciences Center, New Orleans, LA 70112, United States of America

Steven K. Libutti

Affiliations Department of Surgery, Albert Einstein College of Medicine, Bronx, NY 10461, United States of America, Department of Genetics, Albert Einstein College of Medicine, Bronx, NY 10461, United States of America, Albert Einstein Cancer Center, Albert Einstein College of Medicine, Bronx, NY 10461, United States of America

Richard N. Kitsis

richard.kitsis@einstein.yu.edu

Affiliations Department of Medicine (Cardiology), Albert Einstein College of Medicine, Bronx, NY 10461, United States of America, Department of Cell Biology, Albert Einstein College of Medicine, Bronx, NY 10461, United States of America, Wilf Family Cardiovascular Research Institute, Albert Einstein College of Medicine, Bronx, NY 10461, United States of America, Albert Einstein Cancer Center, Albert Einstein College of Medicine, Bronx, NY 10461, United States of America, Einstein-Sinai Diabetes Research Center, Albert Einstein College of Medicine, Bronx, NY 10461, United States of America

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: RNK SKL WMM ZY. Performed the experiments: WMM ZY MZ. Analyzed the data: RNK SKL WMM ZY. Contributed reagents/materials/analysis tools: RNK SKL JSC. Wrote the paper: RNK SKL WMM ZY.