About the Authors

Gregory D. Ferguson

gferguson66@yahoo.com

Affiliation Department of Inflammation Research, Celgene Corporation, San Diego, California, United States of America

Mercedes Delgado

Affiliation Department of Chemistry, Celgene Corporation, San Diego, California, United States of America

Veronique Plantevin-Krenitsky

Affiliation Department of Chemistry, Celgene Corporation, San Diego, California, United States of America

Kristen Jensen-Pergakes

Affiliation Department of Tumor Cell Biology, Pfizer Corporation, San Diego, California, United States of America

R. J. Bates

Affiliation Department of Inflammation Research, Celgene Corporation, San Diego, California, United States of America

Sanaa Torres

Affiliation Department of Inflammation Research, Celgene Corporation, San Diego, California, United States of America

Maria Celeridad

Affiliation Department of Inflammation Research, Celgene Corporation, San Diego, California, United States of America

Heather Brown

Affiliation Department of Pharmacology, Celgene Corporation, San Diego, California, United States of America

Kelven Burnett

Affiliation Department of Pharmacology, Celgene Corporation, San Diego, California, United States of America

Lisa Nadolny

Affiliation Department of Chemistry, Celgene Corporation, San Diego, California, United States of America

Lida Tehrani

Affiliation Department of Chemistry, Celgene Corporation, San Diego, California, United States of America

Garrick Packard

Affiliation Department of Chemistry, Celgene Corporation, San Diego, California, United States of America

Barbra Pagarigan

Affiliation Department of Biochemistry, Celgene Corporation, San Diego, California, United States of America

Jason Haelewyn

Affiliation Department of Biochemistry, Celgene Corporation, San Diego, California, United States of America

Trish Nguyen

Affiliation Department of Biochemistry, Celgene Corporation, San Diego, California, United States of America

Li Xu

Affiliation Department of Inflammation Research, Celgene Corporation, San Diego, California, United States of America

Yang Tang

Affiliation Department of Pharmacology, Celgene Corporation, San Diego, California, United States of America

Matthew Hickman

Affiliation Department of Biochemistry, Celgene Corporation, San Diego, California, United States of America

Frans Baculi

Affiliation Department of Biochemistry, Celgene Corporation, San Diego, California, United States of America

Steven Pierce

Affiliation Department of Biochemistry, Celgene Corporation, San Diego, California, United States of America

Keiji Miyazawa

Affiliation Department of Corporate Planning and Strategy, Kissei Pharmaceutical Company, Matsumoto City, Nagano, Japan

Pilgrim Jackson

Affiliation Department of Biochemistry, Celgene Corporation, San Diego, California, United States of America

Philip Chamberlain

Affiliation Department of Biochemistry, Celgene Corporation, San Diego, California, United States of America

Laurie LeBrun

Affiliation Department of Biochemistry, Celgene Corporation, San Diego, California, United States of America

Weilin Xie

Affiliation Department of Inflammation Research, Celgene Corporation, San Diego, California, United States of America

Brydon Bennett

Affiliation Department of Inflammation Research, Celgene Corporation, San Diego, California, United States of America

Kate Blease

Affiliation Department of Pharmacology, Celgene Corporation, San Diego, California, United States of America

Competing Interests

KJ-P is an employee of Pfizer Corporation and declares no competing interests. KM is an employee of Kissei Pharmaceutical Company and declares no competing interests. This does not alter the authors' adherence to PLOS ONE policies on sharing data and materials. Celgene does have an issued patent for CC-509: US 8299056-B2.

Author Contributions

Conceived and designed the experiments: GDF MD BB K. Blease WX LL MD. Performed the experiments: KJ-P RJB MC LX MH FB ST JH TN SP HB K. Burnett YT BP PJ VP-K LN LT GP. Analyzed the data: PJ PC GDF LL K. Blease MD. Contributed reagents/materials/analysis tools: KM PC. Wrote the paper: GDF MD K. Blease BB LL PC.