About the Authors

Nuria Muñoz-Rivas

Contributed equally to this work with: Nuria Muñoz-Rivas, Manuel Méndez-Bailón, Valentín Hernández-Barrera, Rodrigo Jiménez-García, Ana López-de-Andrés

nmunozr@salud.madrid.org

Affiliation Medicine Department, Hospital Universitario Infanta Leonor, Madrid, Spain

Manuel Méndez-Bailón

Contributed equally to this work with: Nuria Muñoz-Rivas, Manuel Méndez-Bailón, Valentín Hernández-Barrera, Rodrigo Jiménez-García, Ana López-de-Andrés

Affiliation Medicine Department, Hospital Clínico San Carlos, Madrid, Comunidad de Madrid, Spain

Valentín Hernández-Barrera

Contributed equally to this work with: Nuria Muñoz-Rivas, Manuel Méndez-Bailón, Valentín Hernández-Barrera, Rodrigo Jiménez-García, Ana López-de-Andrés

Affiliation Preventive Medicine and Public Health Teaching and Research Unit, Health Sciences Faculty, Rey Juan Carlos University, Alcorcon, Comunidad de Madrid, Spain

José Ma de Miguel-Yanes

‡ These authors also contributed equally to this work.

Affiliation Medicine Department, Hospital Gregorio Marañon, Comunidad de Madrid, Spain

Rodrigo Jiménez-García

Contributed equally to this work with: Nuria Muñoz-Rivas, Manuel Méndez-Bailón, Valentín Hernández-Barrera, Rodrigo Jiménez-García, Ana López-de-Andrés

Affiliation Preventive Medicine and Public Health Teaching and Research Unit, Health Sciences Faculty, Rey Juan Carlos University, Alcorcon, Comunidad de Madrid, Spain

Jesús Esteban-Hernández

‡ These authors also contributed equally to this work.

Affiliation Preventive Medicine and Public Health Teaching and Research Unit, Health Sciences Faculty, Rey Juan Carlos University, Alcorcon, Comunidad de Madrid, Spain

Isabel Jiménez-Trujillo

‡ These authors also contributed equally to this work.

Affiliation Preventive Medicine and Public Health Teaching and Research Unit, Health Sciences Faculty, Rey Juan Carlos University, Alcorcon, Comunidad de Madrid, Spain

Alejandro Alvaro-Meca

‡ These authors also contributed equally to this work.

Affiliation Preventive Medicine and Public Health Teaching and Research Unit, Health Sciences Faculty, Rey Juan Carlos University, Alcorcon, Comunidad de Madrid, Spain

Pilar Carrasco-Garrido

‡ These authors also contributed equally to this work.

Affiliation Preventive Medicine and Public Health Teaching and Research Unit, Health Sciences Faculty, Rey Juan Carlos University, Alcorcon, Comunidad de Madrid, Spain

Javier de Miguel-Díez

‡ These authors also contributed equally to this work.

Affiliation Pneumology Department, Hospital General Universitario Gregorio Marañón, Universidad Complutense de Madrid, Madrid, Spain

Ana López-de-Andrés

Contributed equally to this work with: Nuria Muñoz-Rivas, Manuel Méndez-Bailón, Valentín Hernández-Barrera, Rodrigo Jiménez-García, Ana López-de-Andrés

Affiliation Preventive Medicine and Public Health Teaching and Research Unit, Health Sciences Faculty, Rey Juan Carlos University, Alcorcon, Comunidad de Madrid, Spain

Competing Interests

The authors have the following interests: This study was partly funded by URJC-Banco Santander to the Grupo de Excelencia Investigadora ITPSE (Grant N°30VCPIGI03). There are no patents, products in development or marketed products to declare. This does not alter the authors’ adherence to all the PLOS ONE policies on sharing data and materials, as detailed online in the guide for authors.

Author Contributions

Conceived and designed the experiments: RJG ALA. Performed the experiments: NMR MMB RJG. Analyzed the data: NMR VHB ALA. Contributed reagents/materials/analysis tools: NMR MMB RJG AAM JMMY PCG JMD JEH IJT ALA. Wrote the paper: NMR MMB RJG ALA.