About the Authors

Steffen Bank

stb@mb.au.dk

Affiliations Medical Department, Viborg Regional Hospital, Viborg, Denmark, Biomedicine, University of Aarhus, Aarhus, Denmark

Paal Skytt Andersen

Affiliations Microbiology and Infection Control, Statens Serum Institut, Copenhagen, Denmark, Veterinary Disease Biology, University of Copenhagen, Copenhagen, Denmark

Johan Burisch

Affiliation Department of Gastroenterology, Herlev Hospital, Herlev, Denmark

Natalia Pedersen

Affiliation Department of Gastroenterology, Herlev Hospital, Herlev, Denmark

Stine Roug

Affiliation Department of Gastroenterology, Hvidovre Hospital, Hvidovre, Denmark

Julied Galsgaard

Affiliation Medical Department, Køge Hospital, Køge, Denmark

Stine Ydegaard Turino

Affiliation Medical Department, Hillerød Hospital, Hillerød, Denmark

Jacob Broder Brodersen

Affiliations Medical Department, Sydvestjysk Hospital, Esbjerg, Denmark, Department of medical Gastroenterology, Odense University Hospital, Odense, Denmark

Shaista Rashid

Affiliation Medical Department, Bispebjerg Hospital, Bispebjerg, Denmark

Britt Kaiser Rasmussen

Affiliation Medical Department, Nykøbing Falster Hospital, Nykøbing Falster, Denmark

Sara Avlund

Affiliation Medical Department V, Aarhus University Hospital, Aarhus, Denmark

Thomas Bastholm Olesen

Affiliation Medical Department, Slagelse Hospital, Slagelse, Denmark

Hans Jürgen Hoffmann

Affiliation Department of Respiratory Diseases B, Institute for Clinical Medicine, Aarhus University Hospital, Aarhus, Denmark

Bjørn Andersen Nexø

Affiliation Biomedicine, University of Aarhus, Aarhus, Denmark

Jacob Sode

Affiliations Institute of Regional Health Research, University of Southern Denmark, Odense, Denmark, Department of Autoimmunology and Biomarkers, Statens Serum Institut, Copenhagen, Denmark, Department of Rheumatology, Frederiksberg Hospital, Frederiksberg, Denmark

Ulla Vogel

Affiliation National Research Centre for the Working Environment, Copenhagen, Denmark

Vibeke Andersen

Affiliations Medical Department, Viborg Regional Hospital, Viborg, Denmark, Institute of Regional Health Research, University of Southern Denmark, Odense, Denmark, Research unit for Molecular Diagnostic, Hospital of Southern Jutland Aabenraa, Aabenraa, Denmark, OPEN Odense Patient data Explorative Network, Odense University Hospital, Odense, Denmark

Competing Interests

VA receives compensation as a consultant for Merck & Co., Inc. (MSD), and Janssen. There are no patents, products in development or marketed products to declare. This does not alter the authors’ adherence to all the PLOS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: SB PSA BAN JS UV VA. Performed the experiments: SB JB NP S. Roug JG SYT JBB S. Rashid BKR SA TBO HJH. Analyzed the data: SB PSA BAN JS UV VA. Contributed reagents/materials/analysis tools: SB JB NP S. Roug JG SYT JBB S. Rashid BKR SA TBO HJH. Wrote the paper: SB PSA UV VA. Drafting the article or revising it critically: SB PSA JB NP S. Roug JG SYT JBB S. Rashid BKR SA TBO HJH BAN JS UV VA.