About the Authors

Nathaniel Z. Piety

Current address: Department of Biomedical Engineering, University of Houston, Houston, Texas, United States of America

Affiliation Department of Biomedical Engineering, Tulane University, New Orleans, Louisiana, United States of America

Xiaoxi Yang

Current address: BioMedomics, Inc., Durham, North Carolina, United States of America

Affiliation Department of Biomedical Engineering, Tulane University, New Orleans, Louisiana, United States of America

Julie Kanter

Current address: Department of Pediatrics, Medical University of South Carolina, Charleston, South Carolina, United States of America

Affiliations Sickle Cell Center of Southern Louisiana, Tulane University School of Medicine, New Orleans, Louisiana, United States of America, Department of Pediatrics, Section of Hematology/Oncology, Tulane University School of Medicine, New Orleans, Louisiana, United States of America

Seth M. Vignes

Affiliation Department of Biomedical Engineering, Tulane University, New Orleans, Louisiana, United States of America

Alex George

Affiliation Department of Pediatrics, Section of Hematology-Oncology, Baylor College of Medicine, Houston, Texas, United States of America

Sergey S. Shevkoplyas

sshevkoplyas@uh.edu

Current address: Department of Biomedical Engineering, University of Houston, Houston, Texas, United States of America

Affiliation Department of Biomedical Engineering, Tulane University, New Orleans, Louisiana, United States of America

Competing Interests

SSS, NZP, XY and JK are inventors on a utility PCT application “Paper based diagnostic test” (PCT/US2012/064856, 11/13/2012) claiming priority benefit of US 61/692,994 (8/24/2012) and US 61/558,009 (11/10/2011). SSS is a part-owner of Halcyon Biomedical Incorporated, a company that may benefit from commercialization of the paper-based SCA test. XY is an employee of BioMedomics, Inc., developer of the Sickle SCAN™ test. JK is a consultant to BioMedomics, Inc. and to Daktari Diagnostics, Inc., developer of the density-based SCD-AMPS diagnostic test. SMV and AG declare no potential conflicts of interest. This does not alter the authors' adherence to PLOS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: SSS. Performed the experiments: NZP XY SMV. Analyzed the data: NZP XY SSS. Contributed reagents/materials/analysis tools: SSS. Wrote the paper: NZP XY JK SMV AG SSS. Designed the software used in analysis: NZP. Wrote the clinical protocols, obtained IRB approvals, and enrolled patients: JK AG.