About the Authors

Yuki Muraoka

muraoka@kuhp.kyoto-u.ac.jp

Affiliation Department of Ophthalmology and Visual Sciences, Kyoto University Graduate School of Medicine, Kyoto, Japan

Akitaka Tsujikawa

Affiliation Department of Ophthalmology, Kagawa University Faculty of Medicine, Kagawa, Japan

Ayako Takahashi

Affiliation Department of Ophthalmology and Visual Sciences, Kyoto University Graduate School of Medicine, Kyoto, Japan

Yuto Iida

Affiliation Department of Ophthalmology and Visual Sciences, Kyoto University Graduate School of Medicine, Kyoto, Japan

Tomoaki Murakami

Affiliation Department of Ophthalmology and Visual Sciences, Kyoto University Graduate School of Medicine, Kyoto, Japan

Sotaro Ooto

Affiliation Department of Ophthalmology and Visual Sciences, Kyoto University Graduate School of Medicine, Kyoto, Japan

Kiyoshi Suzuma

Affiliation Department of Ophthalmology and Visual Sciences, Kyoto University Graduate School of Medicine, Kyoto, Japan

Akihito Uji

Affiliation Department of Ophthalmology and Visual Sciences, Kyoto University Graduate School of Medicine, Kyoto, Japan

Nagahisa Yoshimura

Affiliation Department of Ophthalmology and Visual Sciences, Kyoto University Graduate School of Medicine, Kyoto, Japan

Competing Interests

A. Tsujikawa has received grant support from Pfizer, Novartis Pharma K.K., Alcon, and Bayer (unrelated to this study). Kiyoshi Suzuma has received grant support from Novartis Pharma K.K. (unrelated to this study). Nagahisa Yoshimura has received financial support from Topcon Corporation, Nidek and Canon (unrelated to this study) and has provided consultancy services to Nidek. There are no patents, products in development or marketed products to declare. This does not alter the authors' adherence to all the PLOS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: YM. Performed the experiments: YM A. Tsujikawa TM SO. Analyzed the data: YM A. Tsujikawa A. Takahashi YI TM SO KS. Contributed reagents/materials/analysis tools: YM A. Tsujikawa A. Takahashi YI TM SO KS AU NY. Wrote the paper: YM A. Tsujikawa.