Wild Edible Fruit of Prunus nepalensis Ser. (Steud), a Potential Source of Antioxidants, Ameliorates Iron Overload-Induced Hepatotoxicity and Liver Fibrosis in Mice

Dipankar Chaudhuri; Nikhil Baban Ghate; Sourav Panja; Abhishek Das; Nripendranath Mandal

doi:10.1371/journal.pone.0144280

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Peer-reviewed

Research Article

Wild Edible Fruit of Prunus nepalensis Ser. (Steud), a Potential Source of Antioxidants, Ameliorates Iron Overload-Induced Hepatotoxicity and Liver Fibrosis in Mice

Dipankar Chaudhuri ,

Contributed equally to this work with: Dipankar Chaudhuri, Nikhil Baban Ghate

Affiliation Division of Molecular Medicine, Bose Institute, P 1/12, C. I. T. Road, Scheme–VIIM, Kolkata, 700054, West Bengal, India
⨯
Nikhil Baban Ghate ,

Contributed equally to this work with: Dipankar Chaudhuri, Nikhil Baban Ghate

Affiliation Division of Molecular Medicine, Bose Institute, P 1/12, C. I. T. Road, Scheme–VIIM, Kolkata, 700054, West Bengal, India
⨯
Sourav Panja,

Affiliation Division of Molecular Medicine, Bose Institute, P 1/12, C. I. T. Road, Scheme–VIIM, Kolkata, 700054, West Bengal, India
⨯
Abhishek Das,

Affiliation Division of Molecular Medicine, Bose Institute, P 1/12, C. I. T. Road, Scheme–VIIM, Kolkata, 700054, West Bengal, India
⨯
Nripendranath Mandal

* E-mail: mandaln@rediffmail.com

Affiliation Division of Molecular Medicine, Bose Institute, P 1/12, C. I. T. Road, Scheme–VIIM, Kolkata, 700054, West Bengal, India
⨯

Wild Edible Fruit of Prunus nepalensis Ser. (Steud), a Potential Source of Antioxidants, Ameliorates Iron Overload-Induced Hepatotoxicity and Liver Fibrosis in Mice

Dipankar Chaudhuri,
Nikhil Baban Ghate,
Sourav Panja,
Abhishek Das,
Nripendranath Mandal

Published: December 3, 2015
https://doi.org/10.1371/journal.pone.0144280

About the Authors

Dipankar Chaudhuri

Contributed equally to this work with: Dipankar Chaudhuri, Nikhil Baban Ghate

Affiliation Division of Molecular Medicine, Bose Institute, P 1/12, C. I. T. Road, Scheme–VIIM, Kolkata, 700054, West Bengal, India

Nikhil Baban Ghate

Contributed equally to this work with: Dipankar Chaudhuri, Nikhil Baban Ghate

Affiliation Division of Molecular Medicine, Bose Institute, P 1/12, C. I. T. Road, Scheme–VIIM, Kolkata, 700054, West Bengal, India

Sourav Panja

Affiliation Division of Molecular Medicine, Bose Institute, P 1/12, C. I. T. Road, Scheme–VIIM, Kolkata, 700054, West Bengal, India

Abhishek Das

Affiliation Division of Molecular Medicine, Bose Institute, P 1/12, C. I. T. Road, Scheme–VIIM, Kolkata, 700054, West Bengal, India

Nripendranath Mandal

* E-mail: mandaln@rediffmail.com

Affiliation Division of Molecular Medicine, Bose Institute, P 1/12, C. I. T. Road, Scheme–VIIM, Kolkata, 700054, West Bengal, India

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: NM. Performed the experiments: DC NBG SP AD. Analyzed the data: DC NBG. Contributed reagents/materials/analysis tools: NM. Wrote the paper: DC NBG SP NM.

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Antioxidants
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Chelation
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Hydroxyl radicals
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Iron
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Fruits
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Phytochemicals
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Liver fibrosis
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Vitamin C
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