About the Authors

Aaltje Y. Adema

Affiliation Department of Nephrology, VU University Medical Center, Amsterdam, The Netherlands

Frans J. van Ittersum

Affiliation Department of Nephrology, VU University Medical Center, Amsterdam, The Netherlands

Joost G. Hoenderop

Affiliation Department of Physiology, Radboud university medical center Nijmegen, The Netherlands

Martin H. de Borst

Affiliation Department of Internal Medicine, Division of Nephrology, University Medical Center Groningen, Groningen, The Netherlands

Prabath W. Nanayakkara

Affiliation Department of Internal Medicine, VU University Medical Center, Amsterdam, The Netherlands

Piet M. Ter Wee

Affiliation Department of Nephrology, VU University Medical Center, Amsterdam, The Netherlands

Annemieke C. Heijboer

Affiliation Department of Clinical Chemistry, VU University Medical Center, Amsterdam, The Netherlands

Marc G. Vervloet

m.vervloet@vumc.nl

Affiliations Department of Nephrology, VU University Medical Center, Amsterdam, The Netherlands, Institute for Cardiovascular Research VU (ICaR-VU), Amsterdam. The Netherlands

NIGRAM consortium

Membership of the NIGRAM consortium is listed in the Acknowledgments.

Competing Interests

The authors have the following interests: Co-author Dr. Marc G. Vervloet received research support from Fresenius, Shire, Sanofi, AbbVi and Amgen. Dr. Marc G. Vervloet also received speakers fees from Baxter and Amgen and served as consultant for Astellas, Amgen, Fresenius and AbbVie. All other authors declare that no competing interests exist. There are no patents, products in development or marketed products to declare. This does not alter the authors' adherence to all the PLOS ONE policies on sharing data and materials, as detailed online in the guide for authors.

Author Contributions

Conceived and designed the experiments: AA PMTW MGV. Analyzed the data: AA FJvI JGH MHdB MGV. Contributed reagents/materials/analysis tools: PWN ACH. Wrote the paper: AA FJvI MHdB MGV.