About the Authors

Xiaomu Kong

Contributed equally to this work with: Xiaomu Kong, Xuelian Zhang

Affiliation Department of Endocrinology, China-Japan Friendship Hospital, Beijing, China

Xuelian Zhang

Contributed equally to this work with: Xiaomu Kong, Xuelian Zhang

Affiliation Department of Endocrinology, China-Japan Friendship Hospital, Beijing, China

Xiaoyan Xing

Affiliation Department of Endocrinology, China-Japan Friendship Hospital, Beijing, China

Bo Zhang

Affiliation Department of Endocrinology, China-Japan Friendship Hospital, Beijing, China

Jing Hong

Affiliation Department of Endocrinology, China-Japan Friendship Hospital, Beijing, China

Wenying Yang

ywying_1010@163.com

Affiliation Department of Endocrinology, China-Japan Friendship Hospital, Beijing, China

Competing Interests

The authors have the following interests: this study was partly funded by Sanofi (China) Investment Company Limited. There are no patents, products in development or marketed products to declare. This does not alter the authors' adherence to all the PLOS ONE policies on sharing data and materials, as detailed online in the guide for authors.

Author Contributions

Conceived and designed the experiments: WY XK. Performed the experiments: XK XZ XX BZ JH. Analyzed the data: XK XZ XX BZ JH WY. Contributed reagents/materials/analysis tools: XK XZ XX BZ JH WY. Wrote the paper: XK XZ XX BZ JH WY.