About the Authors

Nathalie Assayag-Asherie

Affiliation The Lautenberg Center for Immunology and Cancer Research, IMRIC, The Hebrew University-Hadassah Medical School, Jerusalem 91120, Israel

Dror Sever

Affiliation Department of Endocrinology, Hadassah University Hospital, Ein Kerem, Jerusalem 91120, Israel

Marika Bogdani

Affiliation Matrix Biology Program, Benaroya Research Institute, Seattle, WA, United States of America

Pamela Johnson

Affiliation Matrix Biology Program, Benaroya Research Institute, Seattle, WA, United States of America

Talya Weiss

Affiliation The Lautenberg Center for Immunology and Cancer Research, IMRIC, The Hebrew University-Hadassah Medical School, Jerusalem 91120, Israel

Ariel Ginzberg

Affiliation The Lautenberg Center for Immunology and Cancer Research, IMRIC, The Hebrew University-Hadassah Medical School, Jerusalem 91120, Israel

Sharon Perles

Affiliation The Lautenberg Center for Immunology and Cancer Research, IMRIC, The Hebrew University-Hadassah Medical School, Jerusalem 91120, Israel

Lola Weiss

Affiliation Department of Bone Marrow Transplantation and Cancer Immunotherapy, Hadassah University Hospital Ein Kerem, Hebrew University, Jerusalem, 91120 Israel

Lora Eshkar Sebban

Affiliation The Lautenberg Center for Immunology and Cancer Research, IMRIC, The Hebrew University-Hadassah Medical School, Jerusalem 91120, Israel

Eva A. Turley

Affiliation London Regional Cancer Center, University of Western Ontario, London, ON, Canada

Elimelech Okon

Affiliation LEM laboratories Science Park, Rehovot, Israel

Itamar Raz

Affiliation Diabetes Unit, Hadassah University Hospital, PO Box 12000, Jerusalem 91120, Israel

David Naor

davidn@ekmd.huji.ac.il

Affiliation The Lautenberg Center for Immunology and Cancer Research, IMRIC, The Hebrew University-Hadassah Medical School, Jerusalem 91120, Israel

Competing Interests

This study was funded by Johnson & Johnson. Co-author Elimelech Okon is employed by LEM Laboratories Company. LEM Laboratories Company provided histopathology outsourcing services. There are no patents, products in development, or marketed products to declare. This does not alter the authors' adherence to all the PLOS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: NAA. Performed the experiments: NAA DS MB PJ TW SP LW. Analyzed the data: NAA. Contributed reagents/materials/analysis tools: LES EAT. Wrote the paper: NAA DN. Provided help in graphical illustrations and general statistical analysis: AG. Supervised the clinical aspects of the project: IR. Supervised the entire project and all experiments were performed in his lab: DN. Provided histopathological outsourcing services: EO.