About the Authors

Emily Xie

Affiliation Global Infectious Disease Research Center and the Department of Immunology and Infectious Diseases, The Forsyth Institute, 245 First Street, Cambridge, Massachusetts, United States of America

Abhiroop Kotha

Affiliation Global Infectious Disease Research Center and the Department of Immunology and Infectious Diseases, The Forsyth Institute, 245 First Street, Cambridge, Massachusetts, United States of America

Tracy Biaco

Affiliation Global Infectious Disease Research Center and the Department of Immunology and Infectious Diseases, The Forsyth Institute, 245 First Street, Cambridge, Massachusetts, United States of America

Nikita Sedani

Affiliation Global Infectious Disease Research Center and the Department of Immunology and Infectious Diseases, The Forsyth Institute, 245 First Street, Cambridge, Massachusetts, United States of America

Jonathan Zou

Affiliation Global Infectious Disease Research Center and the Department of Immunology and Infectious Diseases, The Forsyth Institute, 245 First Street, Cambridge, Massachusetts, United States of America

Phillip Stashenko

Affiliations Global Infectious Disease Research Center and the Department of Immunology and Infectious Diseases, The Forsyth Institute, 245 First Street, Cambridge, Massachusetts, United States of America, Department of Oral Medicine, Infection and Immunity, Harvard School of Dental Medicine, Boston, Massachusetts, United States of America

Margaret J. Duncan

Affiliation Department of Microbiology, The Forsyth Institute, 245 First Street, Cambridge, Massachusetts, United States of America

Antonio Campos-Neto

Affiliations Global Infectious Disease Research Center and the Department of Immunology and Infectious Diseases, The Forsyth Institute, 245 First Street, Cambridge, Massachusetts, United States of America, Department of Oral Medicine, Infection and Immunity, Harvard School of Dental Medicine, Boston, Massachusetts, United States of America

Mark J. Cayabyab

mcayabyab@forsyth.org

Affiliations Global Infectious Disease Research Center and the Department of Immunology and Infectious Diseases, The Forsyth Institute, 245 First Street, Cambridge, Massachusetts, United States of America, Department of Oral Medicine, Infection and Immunity, Harvard School of Dental Medicine, Boston, Massachusetts, United States of America

Competing Interests

The authors have a patent pending relating to recombinant S. mitis. U.S. Patent Application Serial No. 13/624,146, Filed: September 21, 2012, Title: A Vaccine and Therapeutic Delivery System, Inventors: Antonio Campos-Neto, Margaret Duncan and Mark Cayabyab. This does not alter the authors' adherence to PLOS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: MC AC MD PS. Performed the experiments: EX AK TB NS JZ MC. Analyzed the data: EX AK TB NS JZ MC. Contributed reagents/materials/analysis tools: MD AC MC. Wrote the paper: EX MC.